Formula I Compounds Enhancing Crop Stress Tolerance

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Solution Overview

Problem

Current methods for crop enhancement often rely on conventional fertilizers or chemicals not specifically designed for plant growth, which may not effectively address all aspects of crop improvement such as plant vigor, stress tolerance, and input use efficiency.

Innovation Solution

Application of a compound of formula (I), which can be fluxametamide, isocycloseram, fluralaner, afoxolaner, or lotilaner, to plants, plant parts, propagation material, or growing loci to enhance crop growth, vigor, and stress tolerance.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fertilizers or non-specific chemicals are used for crop enhancement, then basic nutrient supply is provided, but plant vigor, stress tolerance, and input use efficiency are not effectively improved

Engineering Contradiction:
Improvestress toleranceVSAvoidcrop yield
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent applies compounds with specific molecular structures (formula I with defined R1-R5 groups) that fundamentally change the chemical parameters of plant interaction. These compounds include insecticides like fluxametamide and fluralaner, and acaricides like afoxolaner and lotilaner, which provide dual functionality: protecting plants while enhancing growth parameters such as vigor and stress tolerance, thereby resolving the contradiction between reliability and productivity

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs multi-functional compounds that simultaneously provide pest control and crop enhancement effects. The specified compounds act as both protective agents against pests and growth enhancers, improving plant vigor, stress tolerance, and input use efficiency while maintaining productivity, thus resolving the contradiction through a single agent performing multiple functions

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Productivity

If conventional fertilizers are used, then nutrient supply is provided, but input use efficiency is not improved

Engineering Contradiction:
Improveinput use efficiencyVSAvoidfertilizer input
Core Design Contradiction:
ProductivityVSQuantity of substance

Solution Approach 1:

The patent uses compounds of formula (I) that alter the physiological parameters of plant nutrient uptake and utilization. These compounds enhance the plant's ability to use inputs more efficiently, allowing reduced fertilizer quantities while maintaining or improving productivity, thus resolving the contradiction between input use efficiency and fertilizer quantity

Inventive Principle:
Principle #35Parameter changes

3Reliability

If chemicals not designed for plant growth are used, then pest control is achieved, but plant vigor and quality are not enhanced

Engineering Contradiction:
Improveplant vigorVSAvoidchemical side effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent specifies compounds with particular molecular structures (formula I with R1-R5 being H, Cl, F, Br, CF3, CH3) that change the interaction parameters between the chemical and plant systems. These structurally defined compounds provide pest control while simultaneously enhancing plant vigor and quality, reducing harmful side effects compared to conventional chemicals not designed for dual functionality

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP4142493B1Crop enhancement
Publication Date: 2025.06.18 SYNGENTA CROP PROTECITON AG
  • EP4142493B1 patent drawing
  • EP4142493B1 patent drawing
  • EP4142493B1 patent drawing

AI summary

The present invention relates to a method of enhancing a crop by applying to plants, plant parts, plant propagation material or a plant growing locus, a compound of formula (I), which is a compound of formula (Ia), (Ib), (Ic), (Id), (Ie) or (If): where each R1, R2 and R3 is independently selected from H, Cl, F, Br and CF3; each R4 is independently selected from CH3, Cl, Br and CF3; and each R5 is independently selected from where R6 and R7 are each selected from Cl, Br, CH3, CH2CH3, CF3 and OCF2H; R8 is selected from F and OCH3; R9 is selected from H, CH3 and CH2CH3; and R10 is phenyl optionally substituted by F or Cl; where R11 and R12 are each selected from Cl, Br, CH3, CH2CH3, CF3 and OCF2H; each R13 is independently selected from Cl and Br; each R14 is independently selected H, CH3 and CH2CH3; each R15 is independently selected from H and CN; and each X is independently selected from CH and N; or a composition comprising a compound of formula (I).