Vermin-Repellent Compounds Formula I Long-Lasting Efficacy

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Solution Overview

Problem

Current methods for controlling vermin, such as ticks and fleas, are not completely satisfactory, as they often require frequent application, can be costly, and may lead to resistance in parasites, while existing repellents like DEET have short durations of effectiveness and high volatility.

Innovation Solution

Development of novel compounds of formula (I), which are used in vermin-repellent compositions to deter a variety of pests by altering their behavior, preventing them from attacking or infesting treated areas or animals, with a focus on long-term efficacy and low toxicity.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Duration of action of moving object

If existing repellents like DEET are used, then vermin deterrence is achieved, but the duration of effectiveness is short and volatility is high

Engineering Contradiction:
Improveduration of effectivenessVSAvoidvolatility
Core Design Contradiction:
Duration of action of moving objectVSReliability

Solution Approach 1:

The patent applies parameter changes by modifying the chemical structure of repellent compounds. Specifically, it uses compounds with amino groups having specific pKa values (5-10) and controlled volatility parameters, achieving optimal balance between duration of effectiveness and stability. The molecular weight and functional group composition are adjusted to reduce volatility while maintaining repellent activity.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite materials by formulating vermin-repellent compositions containing multiple active ingredients with complementary properties. The composition includes compounds of formula (I) combined with other repellent substances, creating a synergistic effect that extends duration of effectiveness while reducing individual compound volatility and improving overall reliability.

Inventive Principle:
Principle #40Composite materials

2Reliability

If frequent application is used to maintain effectiveness, then vermin protection is sustained, but cost increases and convenience decreases

Engineering Contradiction:
Improveprotection effectivenessVSAvoidconvenience
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The patent implements continuity of useful action by developing repellent compositions with sustained-release properties. The formulation ensures continuous vermin deterrence through controlled volatility and extended duration of effectiveness, eliminating the need for frequent reapplication and thereby improving convenience while maintaining reliable protection.

Inventive Principle:
Principle #20Continuity of useful action

3Duration of action of moving object

If high concentration of repellent is applied, then duration of effectiveness increases, but toxicity and skin irritation risks increase

Engineering Contradiction:
Improveduration of effectivenessVSAvoidtoxicity
Core Design Contradiction:
Duration of action of moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent applies parameter changes by optimizing the concentration and molecular characteristics of repellent compounds. It selects compounds with specific molecular weights, functional groups, and pKa values that provide extended duration of effectiveness at lower concentrations, thereby reducing toxicity and skin irritation risks while maintaining protective efficacy.

Inventive Principle:
Principle #35Parameter changes

4Reliability

If existing chemical compounds are used, then vermin deterrence is achieved, but resistance in parasites develops over time

Engineering Contradiction:
Improvedeterrence effectivenessVSAvoidparasite resistance
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The patent employs composite materials by formulating compositions with multiple active ingredients having different modes of action. This multi-component approach reduces the likelihood of parasite resistance development, as vermin would need to develop simultaneous resistance to multiple compounds with different mechanisms, thereby maintaining long-term deterrence effectiveness.

Inventive Principle:
Principle #40Composite materials

Data Source

PatentUS7749526B2Vermin-repellant compositions and compounds
Publication Date: 2010.07.06 ELANCO TIERGESUNDHEIT AG
  • US7749526B2 patent drawing
  • US7749526B2 patent drawing
  • US7749526B2 patent drawing

AI summary

Compounds of formula (I) are described for deterring vermin, wherein R is unbranched or branched C1-C15 alkyl, which is unsubstituted or substituted by halogen, cyano or nitro; R1 and R2 are unbranched or branched C1-C12 alkyl, preferably C1-C6 alkyl, which is unsubstituted or substituted by halogen, cyano or nitro; and X and Y, independently of one another, are a straightchain or branched alkylene bridge with 1 to 20 carbon atoms, preferably an alkylene bridge with 1 to 3 carbon atoms, which is unsubstituted or substituted by halogen, cyano or nitro. Furthermore, an essentially non-therapeutical process for deterring vermin is described, which is based on the usage of these compounds, as well as verminrepellent compositions containing these compounds as the active ingredient, and finally the use of these compounds for producing vermin-deterring compositions and their usage in deterring vermin from animals, humans and objects. New compounds within the scope of formula (I) are also described.