Compact Fraction Collector Cooling Rack for Reliable Sample Collection

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Solution Overview

Problem

Existing fraction collectors are complex, expensive, and require significant space, posing challenges in terms of usability and safety.

Innovation Solution

A compact fraction collector design utilizing a linear bearing Y-slide unit and integrated cooling means, with a dispensing head that minimizes splash and requires less space, incorporating a cooling system that allows operation at normal room temperature and reduces the need for climate-controlled environments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a traditional fraction collector apparatus is used, then reliable fraction collection is achieved, but the device complexity and space requirement increase significantly

Engineering Contradiction:
Improvefraction collection reliabilityVSAvoidapparatus complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The apparatus is divided into distinct functional modules: a support system with tray area, a carrier with extension arm for dispensing, and integrated cooling means. Each module performs a specific function independently, simplifying the overall system while maintaining reliability through modular design

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The cooling means are integrated directly into the support system structure, combining the support function and cooling function into a single unified system. This eliminates the need for separate cooling apparatus while ensuring reliable temperature control for fraction collection

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If a traditional fraction collector apparatus is used, then fraction collection is achieved, but the apparatus requires considerable space

Engineering Contradiction:
Improvefraction collection capabilityVSAvoidfootprint
Core Design Contradiction:
ReliabilityVSArea of stationary object

Solution Approach 1:

The carrier and extension arm mechanism operates in a vertical dimension above the tray area, allowing the dispensing head to reach collection vessels without requiring horizontal space for complex mechanical structures. This vertical arrangement significantly reduces the horizontal footprint while maintaining full fraction collection capability

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

Solution Approach 2:

The extension arm is connected to the carrier in a nested arrangement where the extension arm can be retracted into or extended from the carrier structure. This nested design minimizes the space required when the arm is not in use while providing full range of motion when needed

Inventive Principle:
Principle #7Nested doll (Nesting)

3Device complexity

If no integrated cooling means are used, then the apparatus is simpler, but operation requires climate-controlled environments

Engineering Contradiction:
Improveapparatus simplicityVSAvoidoperational flexibility
Core Design Contradiction:
Device complexityVSEase of operation

Solution Approach 1:

The cooling means are merged with the support system structure, creating an integrated unit where the tray area and cooling elements form a single assembly. This integration adds minimal structural complexity while providing comprehensive cooling coverage for all collection vessels

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The integrated cooling means serve multiple functions: they cool the collection vessels during fraction collection, maintain temperature stability for various sample types, and enable operation in diverse environmental conditions. This multi-functionality significantly enhances operational flexibility without proportionally increasing complexity

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution results in a more reliable, easy-to-clean, and cost-effective fraction collector that can operate at room temperature, minimizing splash and reducing the risk of contamination while maintaining fraction integrity.

Implementation Method 1

a motion of said carrier is achieved by a linear bearing Y-slide unit, wherein the linear bearing Y-slide unit is arranged underneath a linear bearing Y-rail

Methodology Applied
Scientific EffectLinear bearing: Ball Bearing

Implementation Method 2

a rack configured to be used in a fraction collector, wherein said rack comprises cooling means configured for surrounding at least one collection vessel

Methodology Applied
Scientific EffectCooling: Cooling

Data Source

PatentUS12551824B2Fraction collector, cooling arangement, and rack for use therewith
Publication Date: 2026.02.17 CYTIVA SWEDEN AB
  • US12551824B2 patent drawing
  • US12551824B2 patent drawing
  • US12551824B2 patent drawing

AI summary

The invention relates to a fraction collector apparatus (100) comprising: a support system (1, 2), a carrier (42) moveably supported by the support system (1, 2), an extension arm (3) connected to the carrier (42), at least one dispensing head (31) for dispensing droplets and moveably connected to the extension arm (3), wherein the dispensing head (31) and (carrier 42) are configured to move relative to the support system in a first plane, a tray area (11) designed to support at least one rack (6, 7), wherein the at least one rack (6, 7) is designed to hold at least one collection vessel (12, 14), wherein motion of said carrier (42) is achieved by a linear bearing Y-slide unit (41) wherein the linear bearing Y-slide unit (41) is arranged underneath a linear bearing Y-rail (40) and wherein the carrier (42) is attached to the linear bearing Y-slide unit (41).