Frozen Composition Spray Delivery for Deeper Skin Penetration

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Solution Overview

Problem

Existing methods for delivering compositions to the skin face challenges in achieving consistent and deep penetration while minimizing skin damage, with conventional application and injection methods being inefficient and invasive.

Innovation Solution

A method and device for freezing a liquid composition using a refrigerant to create a solid state, which is then sprayed onto the skin, ensuring a freeze ratio of at least 5% of the composition reaches the skin in a solid state, utilizing a mixing spray system with a refrigerant container, nozzle, and composition guide to control the freeze ratio.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Length of moving object

If conventional application methods are used to deliver composition to the skin, then the process is simple and non-invasive, but the penetration depth is insufficient and the composition cannot reach deep into the skin

Engineering Contradiction:

Improvepenetration depthVSAvoidoperation simplicity

Core Design Contradiction:

Length of moving objectVSEase of operation

Solution Approach 1:

The patent applies phase transition by freezing the liquid composition into solid frozen particles before spray delivery. This phase change enables the composition to penetrate deeper into the skin as solid particles can penetrate the stratum corneum more effectively than liquid form, while the freezing process occurs automatically during the spray delivery mechanism

Inventive Principle:

Principle #36Phase transitions

Solution Approach 2:

The patent uses a spray delivery system with pneumatic principles to deliver the frozen composition to the skin. The spray mechanism propels the frozen particles at high velocity toward the skin surface, enabling deep penetration without requiring invasive procedures like injections

Inventive Principle:

Principle #29Pneumatics and hydraulics

2Length of moving object

If injection methods are used to deliver composition to the skin, then deep penetration is achieved, but the procedure becomes invasive and causes skin damage

Engineering Contradiction:

Improvepenetration depthVSAvoidskin damage

Core Design Contradiction:

Length of moving objectVSObject-affected harmful factors

Solution Approach 1:

The patent uses phase transition to convert liquid composition into solid frozen particles that can penetrate the skin barrier naturally. This eliminates the need for invasive injection while achieving deep penetration into the dermis layer, as the frozen particles mechanically penetrate the stratum corneum without causing skin damage

Inventive Principle:

Principle #36Phase transitions

Solution Approach 2:

The patent replaces the mechanical injection system with a spray delivery system that uses frozen particles. Instead of using a needle to force composition into the skin (which causes damage), the system sprays frozen particles that naturally penetrate the skin barrier through their solid state properties, substituting a harmful mechanical injection process with a benign spray process

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If the composition is sprayed as liquid state, then the delivery process is simple, but the penetration effectiveness is insufficient

Engineering Contradiction:

Improvepenetration effectivenessVSAvoidsystem complexity

Core Design Contradiction:

ProductivityVSDevice complexity

Solution Approach 1:

The patent incorporates a freezing mechanism into the spray system that automatically transitions the liquid composition into solid frozen particles during the spray process. This phase transition occurs within the spray chamber, enabling enhanced penetration effectiveness without requiring separate freezing and spraying steps, thus the increase in productivity is achieved with minimal additional system complexity

Inventive Principle:

Principle #36Phase transitions

Solution Approach 2:

The patent merges the freezing process and spray delivery process into a single integrated system. The composition is frozen and sprayed in one continuous operation, combining two functions (freezing and spraying) into one device and process step, which improves penetration effectiveness while minimizing the increase in device complexity

Inventive Principle:

Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method enables deeper skin penetration, achieving a significant penetration effect by using frozen composition particles that act like needles, improving the amount of composition absorbed into the dermis compared to conventional methods.

Implementation Method 1

freezing a liquid composition using a refrigerant to create a solid state

Methodology Applied

Scientific EffectFreezing: Freezing

Implementation Method 2

spraying the composition with the refrigerant to the target region, a part of the composition in the liquid state being frozen

Methodology Applied

Scientific EffectHeat transfer: Conduction (thermal)

Data Source

PatentUS20250256079A1Method of providing frozen composition and device therefor

Publication Date: 2025.08.14 RECENSMEDICAL INC

AI summary

Proposed are a method of providing a frozen composition and a device therefor and, more specifically, to a method of spraying a composition in a frozen state to a target region and a device therefor. A composition in a liquid state may be sprayed together with a refrigerant, and the composition may be frozen into a solid state by the refrigerant having a relatively low temperature and may reach the target region. The composition in a solid state may have the effect of improving skin penetration compared to the composition in a liquid state.