Biological Frozen Material Thawing With 60–140 MHz Irradiation

Resolve Bottlenecks,
Find Innovative SolutionsGenerate Solutions

Solution Overview

Problem

Current thawing methods for frozen biological substances, such as blood and cells, are inefficient, leading to performance deterioration, contamination, and prolonged thawing times, which can damage the substances and yield inaccurate experimental data.

Innovation Solution

Irradiating frozen biological substances with electromagnetic waves at 60 to 140 MHz to accelerate thawing and reduce performance deterioration.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of time

If frozen substances are thawed using conventional methods (thermostatic baths, refrigerators, or running water), then the substances can be thawed, but the thawing time is prolonged and the substances suffer performance deterioration

Engineering Contradiction:

Improvethawing timeVSAvoidperformance of thawed substance

Core Design Contradiction:

Loss of timeVSReliability

Solution Approach 1:

The patent replaces conventional thermal conduction-based thawing methods with electromagnetic wave irradiation. The electromagnetic waves directly interact with water molecules in the frozen substance, converting electromagnetic energy to thermal energy through dielectric heating, thereby achieving rapid and uniform thawing without the time loss and performance deterioration associated with conventional methods

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent employs specific electromagnetic wave frequency parameters (60-140 MHz very high frequency range) to optimize the heating effect. By controlling the frequency and power of the electromagnetic waves, the patent achieves efficient energy transfer to the frozen substance, enabling rapid thawing while maintaining substance integrity and avoiding overheating damage

Inventive Principle:

Principle #35Parameter changes

2Temperature

If frozen blood is thawed by heating the surface and conducting heat inward, then the substance can be thawed, but the temperature difference between outer and inner portions increases adversely affecting performance

Engineering Contradiction:

Improvetemperature distributionVSAvoidperformance of thawed substance

Core Design Contradiction:

TemperatureVSReliability

Solution Approach 1:

The electromagnetic waves induce rapid oscillation of water molecules throughout the frozen substance simultaneously. This volumetric heating approach eliminates the temperature gradient problem by heating the entire substance uniformly from the inside out, rather than conducting heat from the surface inward, thus preserving coagulation factor activity and preventing protein denaturation

Inventive Principle:

Principle #18Mechanical vibration

Solution Approach 2:

The patent replaces thermal conduction (heat transfer through material) with electromagnetic radiation (direct energy penetration). The electromagnetic waves penetrate the frozen substance and convert to heat throughout the volume simultaneously, achieving uniform temperature distribution and eliminating the adverse temperature difference between outer and inner portions

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

3Productivity

If frozen blood is thawed using warm water immersion, then the thawing speed increases, but contamination with germs and performance deterioration occur

Engineering Contradiction:

Improvethawing speedVSAvoidcontamination and performance deterioration

Core Design Contradiction:

ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces contact-based thermal transfer (warm water immersion) with non-contact electromagnetic wave irradiation. This eliminates the contamination risk from water contact while maintaining rapid thawing speed. The electromagnetic waves transfer energy through air or vacuum without requiring physical contact, thus preventing germ contamination while achieving fast thawing

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent introduces electromagnetic waves as an intermediary energy carrier between the power source and the frozen substance. This intermediary enables energy transfer without physical contact between the thawing medium and the frozen substance, eliminating contamination risks while maintaining efficient heat transfer and rapid thawing speed

Inventive Principle:

Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method achieves rapid thawing with reduced temperature variations and contamination, preserving the integrity of the biological substances for medical and research use.

Implementation Method 1

irradiating the frozen substance of biological origin with electromagnetic waves at 60 to 140 MHz to accelerate thawing

Methodology Applied

Scientific EffectElectromagnetic radiation heating: Dielectric Heating

Data Source

PatentUS20250268795A1Method for thawing biologically-derived frozen material by very high frequency electromagnetic wave irradiation, cryoprecipitate producing method, and thawing device

Publication Date: 2025.08.28 SMART HUNDRED CORP

AI summary

A thawing method and a thawing apparatus for thawing a frozen substance of biological origin for medicine or research within a shorter time to reduce performance deterioration of the substance by avoiding contamination with germs and reducing temperature variations at thawing. High performance and safety are sought for thawed substances of biological origin particularly for medicine or research. The frozen substance of biological origin for medicine or research is irradiated with electromagnetic waves at 60 to 140 MHz to accelerate thawing and reduce performance deterioration of the frozen substance of biological origin.