Fucoxanthin Purification Using Absorbents to Remove Heavy Metals

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Solution Overview

Problem

Current methods for producing fucoxanthin from seaweeds face challenges due to low content in raw materials, ease of decomposition, and contamination with heavy metals and arsenic, leading to high production costs and safety concerns from using harmful solvents like dimethyl sulfoxide.

Innovation Solution

A method involving the use of an alcohol-water solution for extraction and absorption with absorbents like macroporous resin, polyamide, and alumina to reduce heavy metal and arsenic content, while increasing fucoxanthin concentration, ensuring product safety and cost-effectiveness.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If dimethyl sulfoxide is used as extraction solvent, then fucoxanthin can be extracted from seaweeds, but harmful organic solvent remains in the product reducing safety and increasing production cost

Engineering Contradiction:
Improvefucoxanthin extraction efficiencyVSAvoidharmful organic solvent residue
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and removes harmful substances (heavy metals and arsenic salts) from the fucoxanthin extract through absorption processes using activated carbon and other absorbents, separating these harmful factors from the desired fucoxanthin compound to produce a safe final product

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces absorption agents (activated carbon, macroporous resin, polyamide, alumina) as intermediary substances that selectively bind to and remove harmful components from the extract, facilitating the purification process without directly contacting the final product with harmful solvents

Inventive Principle:
Principle #24Intermediary (Mediator)

2Quantity of substance

If dimethyl sulfoxide is used for extraction, then fucoxanthin can be obtained, but the high boiling point makes it difficult to remove the solvent by conventional operations

Engineering Contradiction:
Improvefucoxanthin yieldVSAvoidsolvent removal difficulty
Core Design Contradiction:
Quantity of substanceVSEase of manufacture

Solution Approach 1:

The patent extracts and removes harmful substances (heavy metals and arsenic salts) from the fucoxanthin extract through absorption processes using activated carbon and other absorbents, separating these harmful factors from the desired fucoxanthin compound to produce a safe final product

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces absorption agents (activated carbon, macroporous resin, polyamide, alumina) as intermediary substances that selectively bind to and remove harmful components from the extract, facilitating the purification process without directly contacting the final product with harmful solvents

Inventive Principle:
Principle #24Intermediary (Mediator)

3Quantity of substance

If conventional extraction methods are used, then fucoxanthin can be produced, but the content of heavy metal and arsenic salt in the product does not accord with food additive standards

Engineering Contradiction:
Improvefucoxanthin contentVSAvoidheavy metal and arsenic salt content
Core Design Contradiction:
Quantity of substanceVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and removes harmful substances (heavy metals and arsenic salts) from the fucoxanthin extract through absorption processes using activated carbon and other absorbents, separating these harmful factors from the desired fucoxanthin compound to produce a safe final product

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces absorption agents (activated carbon, macroporous resin, polyamide, alumina) as intermediary substances that selectively bind to and remove harmful components from the extract, facilitating the purification process without directly contacting the final product with harmful solvents

Inventive Principle:
Principle #24Intermediary (Mediator)

4Object-affected harmful factors

If absorption process is performed to reduce heavy metals and arsenic salt, then product safety is improved, but the process complexity increases

Engineering Contradiction:
Improveheavy metal and arsenic salt contentVSAvoidproduction process complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent extracts and removes harmful substances (heavy metals and arsenic salts) from the fucoxanthin extract through absorption processes using activated carbon and other absorbents, separating these harmful factors from the desired fucoxanthin compound to produce a safe final product

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces absorption agents (activated carbon, macroporous resin, polyamide, alumina) as intermediary substances that selectively bind to and remove harmful components from the extract, facilitating the purification process without directly contacting the final product with harmful solvents

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The method effectively increases fucoxanthin content and reduces heavy metal and arsenic levels, producing a safe and edible extract suitable for industrial production, meeting food additive standards.

Implementation Method 1

performing absorption process of the fucoxanthin extract by using absorbent to reduce the content of heavy metals and arsenic salt contained in the fucoxanthin extract

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

the fucoxanthin extract is extracted from raw material containing fucoxanthin by an alcohol-water solution

Methodology Applied
Scientific EffectLiquid-liquid extraction: Liquid-Liquid Extraction

Data Source

PatentUS8871217B2Method for producing fucoxanthin
Publication Date: 2014.10.28 ALGAE HEALTH SCIENCES BIOTECHNOLOGY CO LTD
  • US8871217B2 patent drawing

AI summary

The present invention provides a method for producing fucoxanthin extract, said method comprising: performing absorption of the fucoxanthin extract by using absorbent and then performing elution to remove heavy metals and arsenic salt contained in the fucoxanthin extract, wherein the absorbent is selected from a group having macroporous resin, polyamide, activated carbon, alumina and a combination thereof. The method for producing fucoxanthin extract according to the present invention, the content of heave metal in the fucoxanthin extract can be reduced, while the content of fucoxanthin in the fucoxanthin extract can increase. In addition, the present invention also provides a fucoxanthin extract obtained by the above method, as well as fucoxanthin products containing the fucoxanthin extract.