Fucoxanthin-Tocotrienol-Fucoidan Composition for Weight Reduction
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Solution Overview
Problem
Current weight reduction methods using fucoxanthin as a single component are not ideal due to limited effectiveness, and there is a need for a composition that synergistically enhances weight reduction functions.
Innovation Solution
A composition combining fucoxanthin extract with tocotrienols and fucoidans, sourced from algae and plants, formulated with pharmaceutically acceptable adjuvants, which can be administered orally in various preparations to promote weight loss by synergistic action.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a single component (fucoxanthin) is used for weight reduction, then the composition is simple and easy to manufacture, but the weight reduction effect is limited and not ideal
Solution Approach 1:
The patent combines fucoxanthin extract with tocotrienols and fucoidans to create a composite composition. This multi-component formulation leverages the synergistic effects of different natural compounds to enhance weight reduction efficacy beyond what a single component can achieve, directly addressing the limitation of using fucoxanthin alone.
Solution Approach 2:
The patent merges multiple bioactive compounds (fucoxanthin, tocotrienols, and fucoidans) into a single composition. By combining these components that work through different mechanisms, the patent achieves a more comprehensive and effective weight reduction effect while maintaining reasonable manufacturing complexity.
2Reliability
If multiple components are combined to enhance weight reduction effect, then the weight reduction efficacy is improved, but the composition becomes more complex and harder to manufacture
Solution Approach 1:
The patent segments the composition into distinct extractable components (fucoxanthin from brown algae, tocotrienols from palm oil or rice bran, and fucoidans from brown algae). Each component can be extracted and purified separately using established methods, then combined in defined ratios, simplifying the manufacturing process despite the multi-component nature of the final product.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The combination of fucoxanthin, tocotrienols, and fucoidans demonstrates a more significant and effective weight reduction effect compared to using each component alone, with decreased body weight and abdominal fat, as shown in experimental data and clinical trials.
Implementation Method 1
The results of studies showed that fucoxanthin regulates high expression of the uncoupling protein (UCP1) gene in the animal white adipose tissue (WAT), causing the decrease of fat contents in the entrails.
Implementation Method 2
Mediated by fucoxanthin, the expression of UCP1 in the WAT expedites the oxidation of fatty acids.
Implementation Method 3
As tocotrienols have an unsaturated side chain, they are able to more effectively penetrate into the organs containing saturated fatty acid layers, such as the brain and liver, and it is easier for them to distribute into the lipid layers of the cell membranes
Implementation Method 4
these special functions of tocotrienols are related to its structure... performing a better functions of anti-oxidation as well as cleaning up free radicals
Implementation Method 5
laminarin is capable of decreasing the superoxide content in the spleen and increasing the activities of superoxide dismutase (SOD) as well as catalase (CAT), thereby achieving antitumor purpose
Data Source
AI summary
A method of reducing a weight of a subject includes administering to the subject in need thereof a composition comprised of fucoxanthin extract and at least one selected from the group consisting of tocotrienol, fucoidan and a combination thereof, wherein the subject is a mammal.