Functional Feed Additives Using Ellagic Acid Cimenol and Alliin

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Solution Overview

Problem

Current animal feed additives lack effective natural compounds that can regenerate intestinal epithelial cells and provide antimicrobial, antifungal, and antiparasitic properties to improve the physiological state of animals.

Innovation Solution

The extraction and combination of ellagic acid from Punica granatum, cimenol from Thymus vulgaris, and alliin from Allium sativum to create functional additives for animal feed, utilizing specific extraction methods to enhance their concentration and stability, ensuring their interaction with the animal's genome for regeneration and pathogen control.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional feed additives are used, then animal feed provides basic nutrition, but they lack effective natural compounds that can regenerate intestinal epithelial cells and provide antimicrobial properties

Engineering Contradiction:
Improveintestinal cell regeneration capabilityVSAvoidfunctional properties of feed additive
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines three distinct natural compounds (ellagic acid from Punica granatum, cimenol from Thymus vulgaris, and alliin from Allium sativum) into a single composite feed additive product. This composite approach allows the additive to simultaneously provide intestinal cell regeneration, antimicrobial, antifungal, and antiparasitic properties, resolving the contradiction between reliability and adaptability.

Inventive Principle:
Principle #40Composite materials

2Manufacturing precision

If extraction methods are used to concentrate active compounds, then the concentration and stability of compounds are enhanced, but the manufacturing process becomes more complex

Engineering Contradiction:
Improveconcentration of active compoundsVSAvoidextraction process complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent employs extraction methods to isolate and concentrate the active compounds (ellagic acid, cimenol, and alliin) from their respective plant sources. This extraction process removes the active principles from the plant material, achieving high concentration and stability while allowing the use of standard extraction equipment and procedures.

Inventive Principle:
Principle #2Taking out (Extraction)

3Object-affected harmful factors

If natural compounds are used to provide antimicrobial and antifungal properties, then pathogen control is improved, but the storage and handling requirements become more stringent

Engineering Contradiction:
Improvepathogen control effectivenessVSAvoidstorage stability of natural compounds
Core Design Contradiction:
Object-affected harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent performs preliminary extraction and concentration of the active compounds during manufacturing, preparing them in advance for stable storage. By pre-concentrating ellagic acid, cimenol, and alliin into a standardized formulation, the product achieves both high pathogen control effectiveness and improved storage stability, eliminating the need for handling large quantities of fresh plant material.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The resulting feed additives effectively regenerate enterocytes, provide 100% kill rates against gastrointestinal pathogens, and maintain nutritional content, offering improved storage and administration ease with enhanced antimicrobial and antifungal properties.

Implementation Method 1

The extraction and combination of ellagic acid from Punica granatum, cimenol from Thymus vulgaris, and alliin from Allium sativum to create functional additives for animal feed, utilizing specific extraction methods to enhance their concentration and stability

Methodology Applied
Scientific EffectExtraction:

Data Source

PatentUS10111449B2Production procedure for a functional feed based in ellagic acid, cimenol and alliin from vegetable extracts to be used as pronutrient in animal feed
Publication Date: 2018.10.30 BIOVET
  • US10111449B2 patent drawing
  • US10111449B2 patent drawing
  • US10111449B2 patent drawing

AI summary

Obtention of aromatic compounds extracted from Punica granatum, Thymus vulgaris and Allium sativum and which have genome interaction capacity for regeneration of the enterocyte, and their use in the manufacture of functional additives for use in animal feed.