Fungicidal Composition with Complex II Inhibitors for Plant Disease Control

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Solution Overview

Problem

Current compositions for controlling plant diseases lack effective solutions for comprehensive control, particularly against plant pathogens with decreased sensitivity to existing fungicides.

Innovation Solution

A composition comprising a specific compound represented by formula (I) combined with one or more mitochondrial electron transport system complex II inhibitors, such as fluxapyroxad, benzovindiflupyr, or pydiflumetofen, is developed to enhance control efficacy against plant diseases.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fungicides are used for plant disease control, then application is simple and cost-effective, but control efficacy decreases against pathogens with reduced sensitivity

Engineering Contradiction:
Improvecontrol efficacyVSAvoidsensitivity to conventional fungicides
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines compound (I) with mitochondrial electron transport system complex II inhibitors (such as fluxapyroxad, benzovindiflupyr, or pydiflumetofen) in a single composition. This merging of two different fungicidal mechanisms creates a synergistic effect that overcomes pathogen resistance to conventional single-mode fungicides, thereby improving control efficacy against pathogens with reduced sensitivity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite fungicidal composition containing compound (I) and complex II inhibitors in specific weight ratios (0.1:99.9 to 50:50). This composite approach integrates multiple active ingredients with different modes of action, enabling the composition to effectively control plant diseases that have developed resistance to individual conventional fungicides.

Inventive Principle:
Principle #40Composite materials

2Device complexity

If single-ingredient fungicides are used, then composition is simple, but control efficacy against multiple pathogens is insufficient

Engineering Contradiction:
Improvecomposition complexityVSAvoidbroad-spectrum control efficacy
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The patent develops a multi-functional composition where compound (I) and complex II inhibitors work together to provide broad-spectrum protection against various plant pathogens including fungi, oomycetes, and bacteria. This single composition can control multiple types of plant diseases simultaneously, eliminating the need for separate applications of different single-ingredient fungicides.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If compound (I) is used alone, then application is straightforward, but control efficacy is limited compared to combined treatment

Engineering Contradiction:
Improvecontrol efficacyVSAvoidcomposition structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent optimizes the weight ratio parameters of compound (I) and complex II inhibitors to achieve maximum synergistic effect. By carefully controlling the concentration parameters (0.1:99.9 to 50:50 weight ratios), the composition achieves enhanced control efficacy while maintaining practical applicability. This parameter optimization allows the composition to overcome pathogen resistance without requiring overly complex formulation structures.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition effectively controls plant diseases by targeting mitochondrial electron transport system complex II, providing broad-spectrum protection against pathogens with reduced sensitivity to conventional fungicides.

Implementation Method 1

one or more mitochondrial electron transport system complex II inhibitor(s) selected from Group B

Methodology Applied
Scientific EffectMitochondrial electron transport:

Data Source

PatentUS20230130546A1Plant disease control composition and plant disease control method
Publication Date: 2023.04.27 SUMITOMO CHEM CO LTD
  • US20230130546A1 patent drawing
  • US20230130546A1 patent drawing
  • US20230130546A1 patent drawing

AI summary

The present invention provides a composition having excellent control efficacy against plant diseases and a method for controlling plant diseases. A composition for controlling a plant disease comprising a compound represented by formula (I)[wherein each symbol represents the same definition as described in the present description] and one or more mitochondrial electron transport system complex II inhibitor(s) selected from Group B has excellent control effects on plant diseases;Group B: a group consisting of fluxapyroxad, benzovindiflupyr, fluindapyr, pydiflumetofen, 3-(difluoromethyl)-N-(2,3-dihydro-1,1,3-trimethyl-1H-inden-4-yl)-1-methyl-1H-pyrazole-4-carboxamide, a compound represented by formula (1), a compound represented by formula (2), and a compound represented by formula (3)