Fungicidal Composition Merging Quinoline Carboxamides and Bacillus Subtilis

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Solution Overview

Problem

Current fungicidal compounds for agriculture lack superior biological activity, spectrum of activity, safety profile, and physico-chemical properties, and often require frequent applications, leading to environmental impact and operator exposure concerns.

Innovation Solution

Development of novel fungicidal compositions comprising a mixture of quinoline (thio)carboxamide compounds and biofungicides like Bacillus subtilis strains, with specific weight ratios and enantiomeric forms, to enhance biological activity and safety while reducing application frequency and environmental impact.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional fungicidal compounds are used, then disease control is achieved, but application frequency must be increased and environmental impact increases

Engineering Contradiction:

Improvedisease control effectivenessVSAvoidresidual activity duration

Core Design Contradiction:

ReliabilityVSDuration of action of moving object

Solution Approach 1:

The patent combines two different fungicidal compounds (compound of formula I and compound of formula II) into a single composition, creating synergistic effects that extend residual activity and reduce application frequency while maintaining disease control effectiveness

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The invention uses composite fungicidal compositions with specific weight ratios (95:5 to 50:50) of two different chemical compounds, leveraging their complementary properties to achieve prolonged protection and reduced environmental impact

Inventive Principle:

Principle #40Composite materials

2Reliability

If higher application rates are used, then biological activity is improved, but operator exposure and environmental impact increase

Engineering Contradiction:

Improvebiological activityVSAvoidoperator exposure

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent optimizes the weight ratio parameters of the two compounds (95:5 to 50:50) to achieve maximum biological activity at reduced application rates, thereby minimizing operator exposure and environmental impact while maintaining efficacy

Inventive Principle:

Principle #35Parameter changes

3Adaptability or versatility

If single compound compositions are used, then composition simplicity is maintained, but spectrum of activity is limited

Engineering Contradiction:

Improvespectrum of activityVSAvoidcomposition complexity

Core Design Contradiction:

Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent merges two fungicidal compounds with different modes of action into a single composition, broadening the spectrum of activity against various phytopathogens while keeping the formulation relatively simple with defined weight ratios

Inventive Principle:

Principle #5Merging (Combining)

Data Source

PatentUS20250098677A1Fungicidal compositions

Publication Date: 2025.03.27 SYNGENTA CROP PROTECITON AG

AI summary

A fungicidal composition comprising a mixture of components (A) and (B), wherein components (A) and (B) are as defined in claim 1, and use of the compositions in agriculture or horticulture for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi.