Synergistic Fungicidal Composition for Asian Soybean Rust Control

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Solution Overview

Problem

Current fungicides are inadequate for effectively controlling Asian soybean rust caused by Phakopsora pachyrhizi, leading to significant yield losses in soybean production.

Innovation Solution

A novel fungicidal composition comprising a compound of formula I, where R is C1-C6 alkyl, C1-C6 alkoxy, or C3-C6 cycloalkyl, and X is CH or N, combined with at least one compound selected from flufenoxadiazam and metarylpicoxamid, is applied to control diseases caused by phytopathogenic fungi.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If customary fungicides are used, then general fungicidal activity is provided, but effectiveness against Phakopsora pachyrhizi (Asian soybean rust) is insufficient

Engineering Contradiction:
Improveeffectiveness against Phakopsora pachyrhiziVSAvoidspectrum of fungal control
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines compound (A) of formula I with compound (B) selected from flufenoxadiazam or metarylpicoxamid to create a synergistic fungicidal composition. This combination specifically targets Phakopsora pachyrhizi while maintaining broad-spectrum activity against other phytopathogenic fungi, resolving the contradiction between specialized effectiveness and general versatility.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite fungicidal system comprising two distinct chemical compounds with different modes of action. Compound (A) of formula I works synergistically with compound (B) to provide both specialized control of Asian soybean rust and broad-spectrum protection against multiple fungal pathogens.

Inventive Principle:
Principle #40Composite materials

2Reliability

If compound (A) of formula I is used alone, then some fungicidal activity is achieved, but effectiveness is substantially enhanced when combined with compound (B)

Engineering Contradiction:
Improvefungicidal effectivenessVSAvoidcomposition complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent merges compound (A) of formula I with compound (B) in a synergistic combination where the two compounds work together to produce enhanced fungicidal effectiveness. The combination achieves substantially greater activity against target fungi than either compound alone, justifying the increased compositional complexity.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention optimizes the ratio and concentration parameters of compounds (A) and (B) to achieve synergistic effects. By carefully controlling the compositional parameters, the patent maximizes fungicidal effectiveness while managing the complexity of the multi-component system.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS20250040549A1Fungicidal compositions
Publication Date: 2025.02.06 SYNGENTA CROP PROTECITON AG
  • US20250040549A1 patent drawing
  • US20250040549A1 patent drawing
  • US20250040549A1 patent drawing

AI summary

A composition suitable for control of diseases caused by phytopathogens comprising (A) a compound of formula (I) wherein R is C1-C6alkyl, C1-C6alkoxy or C3-C6cycloalkyl, and X is CH or N; and (B) at least one compound selected from compounds known for their fungicidal activity; and a method of controlling diseases on useful plants, especially rust diseases on soybeans or cereals.