Intervertebral Fusion Screw With Bone Remodelling Composition

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Solution Overview

Problem

Current intervertebral fusion techniques require open surgery, lengthy bone consolidation periods, and often result in incomplete fusion or pseudoarthrosis, with subsequent instrumentation causing discomfort and requiring removal only after satisfactory bone mineralization.

Innovation Solution

The development of an intervertebral stabilizing screw and a bone remodelling composition that allows for immediate fusion through percutaneous techniques, eliminating the need for subsequent instrumentation and promoting bone formation in difficult conditions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional open surgery and subsequent instrumentation are used to protect the graft during bone consolidation, then intervertebral stability is maintained, but the device complexity and patient discomfort increase

Engineering Contradiction:
Improveintervertebral stabilityVSAvoidsubsequent instrumentation
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines the stabilizing function and the bone graft protection function into a single integrated device - the intervertebral cage with protrusions. The cage body contains the bone graft while the protrusions provide anchoring to adjacent vertebrae, eliminating the need for separate instrumentation devices and reducing overall system complexity while maintaining reliability

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The intervertebral cage serves multiple functions simultaneously: it acts as a bone graft carrier, provides structural support, maintains intervertebral spacing, and through its protrusions provides mechanical anchoring to prevent device migration. This multi-functionality replaces what would traditionally require multiple separate devices including plates, screws, and rods

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If traditional open surgery with bone graft and instrumentation is performed, then intervertebral fusion is achieved, but the surgical invasiveness and recovery time increase

Engineering Contradiction:
Improvefusion success rateVSAvoidsurgical invasiveness
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The device separates the bone graft material from the structural support function by using distinct components - the cage body for graft containment and the protrusions for mechanical anchoring. This segmentation allows each component to be optimized independently and facilitates minimally invasive insertion through percutaneous techniques

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The intervertebral cage acts as an intermediary device that facilitates fusion by providing a structured environment for bone graft incorporation while mechanically bridging the gap between adjacent vertebrae. The cage mediates the interaction between the bone graft and the vertebral bodies, protecting the graft during consolidation

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If metal inserts project from the spinal column to provide stabilization, then intervertebral stability is maintained, but patient discomfort and potential complications increase

Engineering Contradiction:
Improveintervertebral stabilityVSAvoidpatient discomfort
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent extracts the stabilizing function from external projecting metal inserts and integrates it directly into the intervertebral cage structure through protrusions that anchor into the vertebral bodies. This eliminates the need for separate plates, screws, and rods that project from the spinal column, thereby reducing patient discomfort and potential complications associated with prominent hardware

Inventive Principle:
Principle #2Taking out (Extraction)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables immediate and effective intervertebral fusion with reduced surgical invasiveness, shorter recovery times, and improved fusion success rates, while minimizing the need for post-operative instrumentation.

Implementation Method 1

The composition is osteoinductive, osteogenic and osteoconductive

Methodology Applied
Scientific EffectOsteoinduction:

Implementation Method 2

The composition is osteoinductive, osteogenic and osteoconductive

Methodology Applied
Scientific EffectOsteogenesis:

Implementation Method 3

The composition is osteoinductive, osteogenic and osteoconductive

Methodology Applied
Scientific EffectOsteoconduction:

Implementation Method 4

Different types of bone cements are known, generally biocompatible polymers which are polymerised during application. Polymerisation 'in situ' allows application in a liquid state and the subsequent, immediate hardening thereof.

Methodology Applied
Scientific EffectPolymerisation: Photopolymerisation

Data Source

PatentEP3508151B1Intervertebral fusion device comprising an intervertebral stabilising screw and a composition for bone remodelling
Publication Date: 2025.01.29 ENDOSPINE SL
  • EP3508151B1 patent drawingFigure 1
  • EP3508151B1 patent drawingFigure 2
  • EP3508151B1 patent drawingFigure 3

AI summary

The invention relates to an intervertebral fusion device comprising an intervertebral stabilizing screw and a composition for bone remodeling. The intervertebral stabilizing screw comprises: a main body with an axial through-hole and a distal thread that is secured to the bone, located at a distal end of the main body; a hollow proximal secondary body that can slide along the length of the main body; and a travel stop for the proximal secondary body, located on an outer surface of the main body. According to the invention, the proximal secondary body also includes an external thread for securing to the bone, and the main body comprises at least one fill hole, located between the distal thread and the travel stop, for connecting an intervertebral space to the aforementioned axial hole.