GABA Complex Composition for Sleep Quality Without Next-Day Drowsiness
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Solution Overview
Problem
There is a need for a composition that effectively improves sleep quality, alleviates stress, and suppresses daytime sleepiness without the drawbacks of existing prescription drugs or non-prescription sleep inducers, which either have immediate but prolonged effects or require large doses with less pronounced efficacy.
Innovation Solution
A composition comprising γ-aminobutyric acid (GABA) or its salts, hydrates, or solvates, combined with arginine, niacin, or their salts, hydrates, and solvates, in specific weight ratios and dosages, formulated as food or pharmaceutical products to enhance melatonin secretion and alleviate stress.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Speed
If prescription sleeping pills are used, then sleep quality improves immediately, but the drug effect continues the next day and causes tolerance
Solution Approach 1:
The patent combines multiple natural ingredients (GABA, arginine, niacin, and other amino acids) into a composite formulation that works synergistically to improve sleep quality without the prolonged effects and tolerance issues of prescription drugs
Solution Approach 2:
The patent uses specific weight ratios of ingredients (GABA: 50-200mg, arginine: 100-400mg, niacin: 10-50mg) to optimize the sleep-inducing effect while controlling the duration and avoiding next-day residue effects
2Reliability
If non-prescription sleep inducers are used, then no tolerance develops, but large amounts must be taken and the effect is less pronounced
Solution Approach 1:
The patent merges multiple active ingredients that individually have mild sleep-inducing effects into a synergistic combination, where GABA provides the primary sleep-inducing effect, arginine enhances blood flow and nutrient delivery, and niacin supports metabolic processes, achieving a pronounced effect at moderate dosages
Solution Approach 2:
The patent creates a composite nutritional formulation combining GABA, arginine, niacin, and other amino acids in specific proportions to achieve enhanced efficacy compared to single-ingredient supplements
3Productivity
If high dosage of sleep inducers is taken, then sleep effect is more pronounced, but side effects and tolerance increase
Solution Approach 1:
The patent optimizes the dosage parameters of each ingredient within specific ranges (GABA: 50-200mg, arginine: 100-400mg, niacin: 10-50mg) to achieve maximum sleep-inducing efficacy while staying below thresholds that cause side effects or tolerance
Solution Approach 2:
The patent uses arginine and niacin as intermediary substances that enhance the effectiveness of GABA, allowing lower doses of the primary sleep-inducing agent to achieve the desired effect, thereby reducing the risk of side effects
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The composition significantly improves sleep quality, reduces sleep latency, enhances sleep efficiency, alleviates stress, and suppresses daytime sleepiness, as demonstrated by experimental data showing improved melatonin secretion, reduced fatigue, and decreased daytime drowsiness.
Implementation Method 1
The composition according to an embodiment of the present disclosure can improve the sleep quality by increasing melatonin secretion
Data Source
AI summary
The present disclosure relates to a composition for improving sleep quality, including γ-aminobutyric acid (GABA) or a salt, hydrate or solvate thereof; and at least one of arginine, niacin, and salts, hydrates and solvates thereof. The composition for improving sleep quality may improve the sleep quality by increasing melatonin secretion. In addition, in another aspect, the present disclosure provides a composition for alleviating stress, including γ-aminobutyric acid (GABA) or a salt, hydrate or solvate thereof; and at least one of arginine, niacin, and salts, hydrates and solvates thereof.