Gamma Band Brain Stimulation Frequency Sweeping
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Solution Overview
Problem
Current medical devices for treating movement disorders and neurodegenerative impairments, such as Parkinson's disease, face challenges in effectively reestablishing desired gamma frequency band activity in the brain, which is crucial for improving movement and cognitive states, as existing therapies often fail to adequately synchronize and entrain brain oscillations.
Innovation Solution
The technique involves delivering electrical stimulation to the brain at frequencies greater than a selected gamma band frequency, using an implantable device with leads and electrodes, to reestablish gamma frequency band activity, potentially by sweeping frequencies within a range of 1.05 to 3 times the patient-specific or representative gamma frequency, thereby improving brain synchronization and reducing beta frequency band activity.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If electrical stimulation is delivered at frequencies greater than gamma band frequency, then gamma frequency band activity is reestablished and brain synchronization is improved, but device complexity and programming requirements increase
Solution Approach 1:
The patent applies parameter changes by delivering electrical stimulation at frequencies greater than the patient-specific gamma band frequency (e.g., 1.05 to 3 times the gamma frequency) rather than at the gamma frequency itself. This parameter modification enables reestablishment of gamma band activity and improvement of brain synchronization while managing device complexity through systematic frequency selection
Solution Approach 2:
The patent implements dynamics by using patient-specific gamma band frequency determination and adjusting stimulation frequencies accordingly. The system adapts to individual patient characteristics and can dynamically adjust stimulation parameters to optimize therapeutic effect while managing programming complexity through personalized frequency selection
2Reliability
If electrical stimulation is delivered at frequencies greater than gamma band frequency, then beta frequency band activity is reduced and movement control is improved, but energy consumption increases
Solution Approach 1:
The patent applies parameter changes by delivering stimulation at frequencies greater than gamma band frequency (e.g., 1.05 to 3 times gamma frequency) rather than conventional frequencies. This parameter modification achieves superior movement control and beta frequency reduction while the systematic approach to frequency selection helps manage energy consumption through optimized stimulation protocols
3Reliability
If electrical stimulation is delivered at frequencies greater than gamma band frequency, then brain synchronization is enhanced, but programming and operation complexity increase
Solution Approach 1:
The patent applies parameter changes by using frequencies greater than gamma band frequency (systematically selected as 1.05 to 3 times the gamma frequency) to enhance brain synchronization. The method provides a structured approach to frequency selection that improves operational systematicity, though programming requires determination of patient-specific gamma frequencies
Data Source
AI summary
This disclosure describes techniques for delivering electrical stimulation to the brain of a patient at a frequency greater than a selected frequency. The techniques may reestablish gamma frequency band activity within the brain of a patient, and thus improve the patient's movements and cognitive states. In one example, the disclosure is directed to a method that includes selecting a frequency within a gamma frequency band and delivering electrical stimulation at a frequency greater than the selected frequency.