Ganoderma Lucidum Dispersant via Polyphenol Chelation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Ganoderma lucidum powders exhibit poor reconstituability in liquid systems due to interactions between polysaccharides, leading to agglomeration and low extraction efficiency, limiting their use in beverages and milk.

Innovation Solution

A food additive comprising a plant polyphenol and a metal-derived additive, with a controlled mass ratio, binds to and blocks polysaccharides on the surface of Ganoderma lucidum powder particles, enhancing dispersibility and solubility by chelation, allowing for efficient dispersion in aqueous solutions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If Ganoderma lucidum powder is used in liquid systems, then it can be applied in beverages and milk, but it exhibits poor reconstituability and agglomeration due to polysaccharide interactions

Engineering Contradiction:
Improveapplicability in liquid systemsVSAvoidreconstituability
Core Design Contradiction:
Adaptability or versatilityVSStability of the object's composition

Solution Approach 1:

The patent introduces a dispersant comprising plant polyphenol and metal ion as an intermediary substance. The dispersant adsorbs onto the surface of Ganoderma lucidum powder particles, with the polyphenol binding to polysaccharides and metal ions chelating with the polyphenol to control the amount adsorbed. This intermediary layer blocks polysaccharide interactions and prevents agglomeration, enabling the powder to disperse uniformly in liquid systems without direct polysaccharide-polysaccharide contact.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent changes the chemical environment at the powder surface by introducing specific chemical interactions: polyphenol-polysaccharide binding and metal ion-polyphenol chelation. These parameter changes in molecular interactions transform the surface properties of the powder particles, converting them from a state prone to agglomeration to a state that promotes dispersion and prevents re-agglomeration in liquid media.

Inventive Principle:
Principle #35Parameter changes

2Quantity of substance

If hot water extraction is used to obtain Ganoderma lucidum extract solution, then polysaccharides and triterpenoids can be extracted, but the extraction efficiency is low and active ingredients are lost

Engineering Contradiction:
Improveextraction of polysaccharides and triterpenoidsVSAvoidextraction efficiency
Core Design Contradiction:
Quantity of substanceVSProductivity

Solution Approach 1:

The patent applies preliminary ultra-fine crushing to the Ganoderma lucidum fruiting bodies before extraction, reducing particle size to 1-10 μm. This preliminary size reduction dramatically increases the surface area and porosity of the material, enabling subsequent extraction methods (whether hot water or cold water) to access and extract active ingredients much more efficiently, thereby resolving the low extraction efficiency problem.

Inventive Principle:
Principle #10Preliminary action

3Ease of operation

If Ganoderma lucidum powder is dispersed in aqueous system, then it can be used in beverages, but the powder agglomerates due to polysaccharide interaction

Engineering Contradiction:
Improvedispersibility in liquidVSAvoiduniformity of dispersion
Core Design Contradiction:
Ease of operationVSStability of the object's composition

Solution Approach 1:

The dispersant acts as a mediator between the Ganoderma lucidum powder and the aqueous medium. The polyphenol component binds to polysaccharides on the powder surface, while metal ions chelate with the polyphenol, creating a controlled adsorption layer. This intermediary structure prevents direct polysaccharide-polysaccharide interactions that cause agglomeration, while also preventing powder-matrix interactions that would cause re-agglomeration, thereby achieving stable, uniform dispersion.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent creates a composite structure at the powder surface by combining plant polyphenol and metal ion in specific mass ratios (50-2500:0.1-0.2). This composite dispersant system leverages the complementary properties of both components: the polyphenol's ability to bind polysaccharides and the metal ion's chelation capability, creating a synergistic effect that provides superior dispersion stability compared to either component alone.

Inventive Principle:
Principle #40Composite materials

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution enables rapid and homogeneous dispersion of Ganoderma lucidum powder in liquid systems, improving extraction efficiency and flavor, while ensuring safety and health benefits, and allowing for the production of instant products like milk and beverage additives.

Implementation Method 1

a plant polyphenol binds to and adsorbs polysaccharides on the surface of Ganoderma lucidum powder particles

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

an amount of the polyphenol adsorbed on the surface is controlled through metal ion chelation

Methodology Applied
Scientific EffectChelation:

Data Source

PatentUS20240415159A1Food additive for dispersing ganoderma lucidum powder and method for rapidly dispersing ganoderma lucidum powder
Publication Date: 2024.12.19 INNOVATION CENTER OF YANGTZE RIVER DELTA ZHEJIANG UNIVERSITY

AI summary

Provided are a food additive for dispersing a Ganoderma lucidum powder and a method for rapidly dispersing a Ganoderma lucidum powder. The food additive for dispersing a Ganoderma lucidum powder includes a plant polyphenol and a metal-derived food additive in a mass ratio of (50-2,500):(0.1-0.2). The method for rapidly dispersing a Ganoderma lucidum powder with the food additive includes: mixing an aqueous solution of the plant polyphenol with the Ganoderma lucidum powder to obtain a Ganoderma lucidum/polyphenol mixed solution; and thoroughly mixing an aqueous solution of the metal-derived food additive with the Ganoderma lucidum/polyphenol mixed solution. The non-covalent binding of the plant polyphenol to Ganoderma lucidum polysaccharides can promote the adsorption of the plant polyphenol on a surface of Ganoderma lucidum powder particles to hinder the direct contact among the polysaccharides on the surface of Ganoderma lucidum powder particles, thereby improving the dispersion of the Ganoderma lucidum powder particles.