Gas-Filled Submucosal Bleb for Safe Endoscopic Resection
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Solution Overview
Problem
Existing internal surgical procedures face challenges in removing lesions such as superficial tumors and polyps from internal body locations due to their low profile relative to surrounding tissue, often risking injury to the underlying muscularis propria during resection without a submucosal cushion.
Innovation Solution
The use of pressurized gas to create a gas-filled submucosal space, which provides a higher and more pronounced tissue separation, allowing for effective 'inside-out' resection using a resection device that pierces the tissue from within the bleb, reducing the risk of perforating the underlying tissue, and the deployment of a resection barrier like paraffin to further protect the tissue during cutting.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If conventional resection methods are used without submucosal cushion, then the procedure is simpler, but the risk of injuring the underlying muscularis propria increases
Solution Approach 1:
The patent applies beforehand cushioning by injecting gas into the submucosal space to create a cushion that lifts the lesion away from the muscularis propria before resection occurs. This pre-established cushion protects the underlying muscle layer during the cutting process, directly resolving the contradiction between procedural simplicity and safety.
2Stability of the object's composition
If liquid is used to form submucosal cushion, then the cushion is stable, but the tissue separation is less pronounced
Solution Approach 1:
The patent changes the physical parameter of the cushioning medium from liquid to gas. Gas provides both stability (maintaining cushion formation) and superior tissue separation (creating more pronounced lifting effect), thereby resolving the contradiction between cushion stability and tissue separation height.
3Ease of operation
If resection is performed from outside the bleb, then the procedure is conventional, but the risk of perforating underlying tissue increases
Solution Approach 1:
The patent inverts the conventional resection approach by performing the cutting action from inside the bleb outward, rather than from outside inward. This inside-out resection method reduces the risk of perforating the underlying tissue while maintaining procedural feasibility, directly addressing the contradiction between ease of operation and safety.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method enables safer and more effective resection of lesions by maintaining tissue separation and reducing the risk of perforating the underlying muscularis propria, facilitating precise tissue removal with reduced bleeding and improved control.
Implementation Method 1
delivering gas into the mucosal tissue at a selected site through the distal end of the gas delivery lumen, wherein the gas is delivered at a gas pressure greater than the ambient atmospheric pressure
Data Source
AI summary
Apparatus and methods for internal surgical procedures are disclosed. The apparatus and methods may involve supporting internal body locations, creating submucosal separations (blebs), and/or for resecting mucosal tissue separated from underlying tissue by a bleb.