Gas Mixture Generator with Permeation Module for Oxygen Control

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Solution Overview

Problem

Existing methods struggle to create a ternary gas mixture of nitrous oxide (N2O), oxygen (O2), and nitrogen (N2) with controlled O2 concentration, particularly at 30 mol %, while minimizing the number of pressurized gas sources for home use, especially for patients with comorbidities like chronic cardiac insufficiency or chronic obstructive pulmonary disease.

Innovation Solution

A gas mixture generator apparatus with a permeation module using hollow fibers to separate gas mixtures, controlled by solenoid valves and sensors, adjusts the N2O and O2 concentrations by selectively permeating gases through a membrane, allowing for a single cylinder to produce a non-hypoxic premix with adjustable N2O content.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If a 50% N2O/50% O2 premix is used from a single cylinder, then the device complexity is reduced, but the oxygen concentration cannot be controlled to avoid hyperoxia in patients with comorbidities

Engineering Contradiction:
Improvenumber of gas sourcesVSAvoidhyperoxia risk
Core Design Contradiction:
Device complexityVSObject-affected harmful factors

Solution Approach 1:

The patent employs a permeation module with hollow fibers containing a selective membrane that allows N2O to permeate through while blocking O2. This porous material approach enables the system to selectively separate N2O from the 50% N2O/50% O2 premix, reducing oxygen concentration to safe levels while maintaining device simplicity by using only one gas cylinder.

Inventive Principle:
Principle #31Porous materials

2Object-affected harmful factors

If the oxygen concentration is reduced to 30% to prevent hyperoxia, then patient safety is improved, but creating the ternary mixture requires multiple pressurized gas sources increasing device complexity

Engineering Contradiction:
Improvehyperoxia preventionVSAvoidnumber of gas sources
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The permeation module acts as an intermediary device between the single N2O/O2 cylinder and the patient. It selectively removes N2O from the premix through membrane permeation, allowing the system to achieve the desired 30% O2 concentration without requiring separate O2 and N2 cylinders, thus preventing hyperoxia while maintaining device simplicity.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Ease of operation

If a single cylinder with 50% N2O/50% O2 is used, then ease of operation is improved, but the ability to control N2O concentration independently of O2 concentration is lost

Engineering Contradiction:
Improvesimplicity of gas supplyVSAvoidindependent concentration control
Core Design Contradiction:
Ease of operationVSAdaptability or versatility

Solution Approach 1:

The system changes the concentration parameters dynamically by controlling the permeation rate of N2O through the membrane. By adjusting operational parameters such as pressure and flow rate through the permeation module, the system can independently control the final N2O concentration in the delivered mixture while maintaining a fixed safe O2 concentration of 30%, thus providing adaptability without compromising ease of operation.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The apparatus effectively generates a gas mixture with precise O2 and N2O concentrations, ensuring patient safety by minimizing oxygen levels and reducing the number of gas sources required, suitable for home use and reducing the risk of hyperoxia or hypoxemia.

Implementation Method 1

at least one permeation module arranged on the second gas line, the said permeation module comprising a feed port in fluidic communication with the second gas line, a retentate port and a permeate port

Methodology Applied
Scientific EffectPermeation: Permeation

Data Source

PatentUS11517703B2Apparatus and installation for supplying a gas mixture to a patient
Publication Date: 2022.12.06 LAIR LIQUIDE SA POUR LETUDE & LEXPLOITATION DES PROCEDES GEORGES CLAUDE
  • US11517703B2 patent drawing

AI summary

An apparatus (1) for supplying a gas mixture to a patient, having a gas inlet line (30) with a gas inlet orifice (30a) that splits into a first gas line (31) and a second gas line (32); at least one permeation module (33) arranged on the second gas line (32), the said permeation module (33) having a feed port (33a) in fluidic communication with the second gas line (32), a retentate port (33b) and a permeate port (33c); a third gas line (34) in fluidic communication with the retentate port (33b) of the permeation module (33); a fourth gas line (35) in fluidic communication with the permeate port (33c) of the permeation module (33), and coupling fluidically to the said first gas line (31); and a source (360) of air in fluidic communication with the first gas line (31) and the fourth gas line (35).