Gastrointestinal Vibrating Capsule for Circadian Jetlag Mitigation

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Solution Overview

Problem

Existing gastrointestinal treatment systems do not effectively mitigate the effects of jetlag, particularly for travelers, and there is a need for a system that can adapt to different time zones and gastric cycles to provide targeted mechanical stimulation.

Innovation Solution

A gastrointestinal treatment system comprising a vibrating capsule that is activated at predetermined times based on the subject's circadian cycle and gastric pH profile, using a control mechanism to operate in a vibrating mode to provide mechanical stimulation to the gastrointestinal tract.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the capsule provides continuous mechanical stimulation, then gastrointestinal treatment effectiveness is improved, but energy consumption increases and jetlag mitigation is reduced

Engineering Contradiction:
Improvegastrointestinal treatment effectivenessVSAvoidenergy consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The capsule implements periodic vibration cycles with alternating active and inactive periods. The control mechanism activates the vibrating agitation mechanism for specific durations (e.g., 10-60 seconds) at predetermined times, then deactivates it. This periodic operation maintains treatment effectiveness by stimulating gastrointestinal motility at critical moments while significantly reducing overall energy consumption compared to continuous operation.

Inventive Principle:
Principle #19Periodic action

Solution Approach 2:

The control mechanism uses timing mechanisms and sensors to activate the vibrating agitation mechanism at predetermined times based on circadian rhythms and gastric pH profiles before gastrointestinal events occur. This preliminary action ensures mechanical stimulation is applied at optimal moments to trigger bowel movements or digestive processes, maximizing treatment effectiveness while minimizing energy usage.

Inventive Principle:
Principle #10Preliminary action

2Adaptability or versatility

If the capsule activates at multiple predetermined times, then jetlag mitigation and gastrointestinal health improvement are enhanced, but device complexity increases

Engineering Contradiction:
Improvejetlag mitigation capabilityVSAvoidcontrol mechanism complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The control mechanism is designed with multi-functionality to handle multiple predetermined activation times, circadian rhythm synchronization, and gastric pH profile adaptation within a single integrated system. The timing mechanism and sensor array work together to automatically determine optimal activation moments without requiring complex external control systems, thereby enhancing jetlag mitigation capability while keeping device complexity manageable.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The capsule employs self-service through integrated sensors (illumination, temperature, motion detectors) that automatically detect environmental and physiological conditions to trigger vibration at appropriate times. This self-determination capability allows the capsule to adapt to different time zones and individual circadian patterns without requiring complex programming or external intervention, improving versatility while maintaining relatively simple device architecture.

Inventive Principle:
Principle #25Self-service

3Measurement precision

If the capsule uses sensors to detect activation moments, then precision of timing is improved, but device complexity and manufacturing cost increase

Engineering Contradiction:
Improveactivation timing precisionVSAvoidmanufacturing simplicity
Core Design Contradiction:
Measurement precisionVSEase of manufacture

Solution Approach 1:

The capsule utilizes periodic sensing intervals where illumination, temperature, and motion sensors check for activation conditions at regular intervals rather than continuously monitoring. This periodic detection approach achieves sufficient timing precision for triggering vibrations at the correct moments while reducing computational burden and manufacturing complexity compared to continuous high-precision monitoring systems.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The system effectively mitigates jetlag symptoms by providing mechanical stimulation at specific times, reducing acute constipation and aligning with the subject's biological rhythms, thereby improving gastrointestinal health.

Implementation Method 1

the vibrating agitation mechanism, in a first vibrating mode of operation, exerts forces on the housing, thereby to cause vibrations

Methodology Applied
Scientific EffectMechanical vibration: Vibration

Data Source

PatentEP3773407B1Gastrointestinal treatment system including a vibrating capsule, and method of use thereof
Publication Date: 2025.08.27 VIBRANT
  • EP3773407B1 patent drawingFigure 1
  • EP3773407B1 patent drawingFigure 2
  • EP3773407B1 patent drawingFigure 3

AI summary

A gastrointestinal treatment system including a gastrointestinal capsule adapted to treat a subject following ingestion of the gastrointestinal capsule. The gastrointestinal capsule includes: (a) a housing; (b) a vibrating agitation mechanism, powered by the battery, the vibrating agitation mechanism adapted such that, in a first vibrating mode of operation, the housing exerts vibrations on an environment surrounding the capsule; (c) a power supply disposed within the housing and adapted to power the vibrating agitation mechanism; and (d) a control mechanism adapted, in response to receipt of an activation input, to activate the vibrating agitation mechanism to operate in the first vibrating mode of operation at at least one predetermined time of day. The system and method may be used to treat an ailment of the gastrointestinal tract and/or to mitigate at least one symptom of jetlag in a subject travelling from an origin location to a destination location.