Assessing Gas Chromatograph Consumable Degradation via Indicator Signal

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Solution Overview

Problem

Existing methods for assessing consumable parts in gas chromatographs and mass analyzers do not adequately account for the varying degree of degradation or contamination caused by the properties of the samples being measured, leading to inaccurate assessment of consumable part consumption.

Innovation Solution

A method involving mass spectrometric analysis of a sample containing indicator substances, where the signal intensity is compared to a preset reference to assess the degree of consumption of consumable parts in contact with the sample, such as septums, inserts, and columns.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If the degree of consumption is assessed based only on degree of use (time, number of times, amount), then the assessment method is simple, but the assessment accuracy is insufficient because it does not account for sample properties affecting degradation

Engineering Contradiction:
Improveassessment accuracyVSAvoidassessment method complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent introduces indicator substances as intermediaries to assess the degree of consumption. These indicator substances are subjected to the same degradation or contamination processes as the consumable parts, and their signal intensity changes serve as a proxy measure for the consumable part's condition, thereby improving assessment accuracy without directly monitoring the consumable parts themselves

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the mechanical/time-based assessment system with a mass spectrometric analysis system. Instead of tracking usage parameters (time, number of operations), the system uses mass spectrometry to detect signal intensity changes of indicator substances, providing a more accurate chemical/physical basis for consumption assessment

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Reliability

If consumable parts are replaced based on scheduled dates calculated from usage data, then replacement timing can be predicted, but actual replacement needs may be missed because sample properties are not considered

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidreplacement timing accuracy
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent implements a feedback mechanism where the signal intensity of indicator substances is continuously monitored and compared against reference values. This feedback loop provides real-time information about the actual condition of consumable parts, allowing dynamic adjustment of replacement timing based on actual degradation rather than predetermined schedules

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent uses indicator substances that undergo degradation or contamination in advance alongside the consumable parts. By monitoring these indicator substances before the consumable parts reach critical failure points, the system can predict and prepare for timely replacement, preventing measurement accuracy degradation

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for a precise assessment of consumable part degradation or contamination, enabling timely replacement and maintaining analyzer accuracy.

Implementation Method 1

a mass spectrometric analysis of the sample for assessment exiting from the gas chromatograph is performed with a mass analyzer

Methodology Applied
Scientific EffectMass spectrometry:

Data Source

PatentEP4467985A1Method for assessing degree of consumption of consumable part of gas chromatograph and mass analyzer
Publication Date: 2024.11.27 SHIMADZU CORP
  • EP4467985A1 patent drawingFigure 1
  • EP4467985A1 patent drawingFigure 2
  • EP4467985A1 patent drawingFigure 3

AI summary

Provided is a method for appropriately assessing the degree of consumption of a consumable part provided at a position where the part comes in contact with a sample in a gas chromatograph or mass analyzer. A sample for assessment containing an indicator substance is passed through a gas chromatograph including the consumable part concerned, and a mass spectrometric analysis of the sample for assessment exiting from the gas chromatograph is performed with a mass analyzer. Alternatively, a mass spectrometric analysis of a sample for assessment containing an indicator substance is performed by using a mass analyzer including the consumable part concerned. A signal intensity of the indicator substance is acquired from the result of the mass spectrometric analysis. The degree of consumption of the consumable part is assessed by comparing the acquired signal intensity with a preset reference signal intensity.