Gas Chromatography Controller with Predictive Diagnostic Module

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Solution Overview

Problem

Gas chromatography (GC) systems face challenges in predictive maintenance and troubleshooting, leading to inefficient hardware replacement and downtime due to lack of automated tools that can specifically address performance degradation and failures, relying on user experience and external guides that may not be instrument-specific.

Innovation Solution

A method and system for GC that utilizes a chromatographic model to simulate separations, collect performance data, and perform monitoring to predict maintenance needs, incorporating a diagnostic and predictive module for automated troubleshooting and notification, leveraging chromatographic performance monitoring and modeling to guide users in maintaining the instrument.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If automated diagnostic and predictive maintenance modules are implemented, then maintenance efficiency and system reliability are improved, but device complexity increases

Engineering Contradiction:
Improvesystem reliabilityVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The controller is designed to perform multiple functions: it controls the GC system operation, generates simulated chromatographic separations using chromatographic models, performs chromatographic performance monitoring by comparing actual vs. simulated data, executes automated troubleshooting procedures, and predicts maintenance needs. This multi-functionality integrates previously separate diagnostic tools into the existing controller, improving reliability while minimizing additional hardware complexity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system performs self-diagnosis and self-monitoring by automatically comparing actual chromatographic separations with simulated ones, identifying performance deviations, and predicting maintenance requirements without external intervention. The automated troubleshooting procedure guides users through diagnostic steps based on system-self-identified issues, enabling the system to service itself and reduce downtime.

Inventive Principle:
Principle #25Self-service

2Measurement precision

If external stand-alone troubleshooting tools are used, then diagnostic capability is provided, but measurement precision and instrument-specific accuracy are reduced

Engineering Contradiction:
Improvediagnostic accuracyVSAvoiddevice complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent merges the troubleshooting and diagnostic capabilities with the GC system controller itself. The controller integrates chromatographic model generation, performance monitoring, and automated troubleshooting into a unified system. This eliminates the need for separate external diagnostic tools and ensures that all diagnostic functions are specifically tailored to the instrument's unique configuration, improving measurement precision and diagnostic accuracy.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The chromatographic model acts as an intermediary between the controller and the actual chromatographic separation process. By simulating expected separation outcomes based on instrument configuration and comparing them with actual results, the model provides a reference framework that enhances diagnostic precision without requiring external tools.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Productivity

If hardware is replaced based on standard operating procedures at fixed intervals, then maintenance scheduling is simplified, but productivity decreases due to unnecessary replacements and downtime

Engineering Contradiction:
ImproveproductivityVSAvoidextent of automation
Core Design Contradiction:
ProductivityVSExtent of automation

Solution Approach 1:

The system performs preliminary diagnostic actions by continuously monitoring chromatographic performance and comparing it with simulated separations. Before hardware replacement becomes necessary, the automated troubleshooting procedure identifies and addresses software-configurable issues, adjusting operational parameters to restore optimal performance. This preliminary intervention prevents unnecessary hardware replacements and maximizes productivity by keeping the system operational longer.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The maintenance approach transitions from static, time-based scheduling to dynamic, condition-based maintenance. The system continuously adapts its diagnostic and predictive functions based on actual instrument performance data, adjusting maintenance recommendations in real-time. This dynamic approach optimizes productivity by performing maintenance only when actually needed rather than following fixed intervals.

Inventive Principle:
Principle #15Dynamics

4Loss of time

If users manually analyze performance data to determine maintenance needs, then flexibility in decision-making is maintained, but loss of time increases due to manual investigation

Engineering Contradiction:
Improveloss of timeVSAvoidextent of automation
Core Design Contradiction:
Loss of timeVSExtent of automation

Solution Approach 1:

The system implements automated feedback loops where chromatographic performance data is continuously collected, compared with simulated separations, and analyzed to generate real-time diagnostic information. The automated troubleshooting procedure provides immediate feedback to users with specific maintenance recommendations based on analyzed performance deviations. This eliminates time-consuming manual data analysis while maintaining informed decision-making through system-generated insights.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The manual mechanical process of analyzing performance data and determining maintenance needs is replaced with automated computational processes. The controller automatically executes chromatographic models, compares simulated versus actual separations, identifies performance issues, and generates troubleshooting recommendations. This substitution of manual analysis with automated computational analysis dramatically reduces time loss while maintaining or improving decision quality.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach reduces unexpected downtime and improves user experience by providing proactive maintenance, optimizing chromatographic performance, and ensuring that maintenance tasks are targeted and effective, thereby enhancing the reliability and efficiency of GC systems.

Implementation Method 1

Gas chromatography (GC) is used to analyze and detect the presence of many different substances in a sample. The function of a gas chromatograph is to separate the components of a chemical sample, known as analytes

Methodology Applied
Scientific EffectChromatography: Chromatography

Implementation Method 2

The column can contain a stationary phase that interacts with the sample to separate the components

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentUS20240011954A1Gas chromatography systems and methods with diagnostic and predictive module
Publication Date: 2024.01.11 AGILENT TECHNOLOGIES INC
  • US20240011954A1 patent drawing
  • US20240011954A1 patent drawing
  • US20240011954A1 patent drawing

AI summary

The present invention provides a gas chromatography system (GC) including a GC column configured for a chromatographic separation of a sample comprising one or more analytes, a GC detector connected to the exit of the GC column, and a controller connected to the GC system. The controller is configured to generate a simulated chromatographic separation using a chromatographic model that calculates at least one chromatographic parameter of the analyzed sample. The controller further configured to execute a chromatographic separation of the sample and execute chromatographic performance monitoring that includes a comparison of at least one chromatographic parameter to the simulated chromatographic separation and/or reference chromatographic separation, determine if at least one chromatographic parameter has fallen outside of a performance control limit and/or predict if the chromatographic parameter will fall outside the performance control limit, and perform an automated GC troubleshooting procedure to determine the cause of the performance issue.