Gel-Based Biosensor for Airborne Biomolecule Detection

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Conventional biosensors require liquid samples and detection platforms, limiting their ability to detect airborne biomolecules effectively and efficiently.

Innovation Solution

Development of portable biosensors with a gel-based detection platform that includes a housing, a sensing component, and an optional sample capture component, utilizing electrolytic gel and electrodes to detect impedance changes caused by biomolecule interactions, allowing for direct detection of airborne biomolecules without the need for liquid samples.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If liquid-based detection platforms are used, then biosensors can detect biomolecules, but they cannot directly detect airborne biomolecules

Engineering Contradiction:
Improvedetection capability for airborne biomoleculesVSAvoidsample preparation requirements
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent changes the physical state parameter of the detection medium from liquid to gel, enabling direct detection of airborne biomolecules while eliminating the need for liquid sample preparation. The gel-based platform allows biomolecules to be detected in their native airborne state without requiring liquidification or other sample preparation steps.

Inventive Principle:
Principle #35Parameter changes

2Productivity

If conventional liquid-based biosensors are used, then detection can be performed, but sample preparation is required

Engineering Contradiction:
Improvedetection speedVSAvoidsample preparation time
Core Design Contradiction:
ProductivityVSLoss of time

Solution Approach 1:

The patent extracts and eliminates the sample preparation step entirely by using a gel-based detection platform that accepts airborne biomolecules directly. This removes the time-consuming preparation process while maintaining detection capability, thereby increasing overall productivity.

Inventive Principle:
Principle #2Taking out (Extraction)

3Ease of operation

If gel-based detection platform is used, then direct detection of airborne biomolecules is enabled, but device complexity increases

Engineering Contradiction:
Improvesample processing simplicityVSAvoidsensing component structure
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The gel-based sensing component serves multiple functions simultaneously: it acts as the detection medium, provides structural support for the bio-component, enables direct airborne sample uptake, and facilitates impedance-based signal detection. This multi-functionality reduces the need for separate components, thereby simplifying the overall device despite the advanced gel-based technology.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables rapid, specific, and direct detection of airborne biomolecules, providing immediate results and reducing the need for sample preparation, making it suitable for various applications including national security and community safety.

Implementation Method 1

utilizing electrolytic gel and electrodes to detect impedance changes caused by biomolecule interactions

Methodology Applied
Scientific EffectImpedance detection: Electrical Resistance

Data Source

PatentUS8399262B2Biosensor
Publication Date: 2013.03.19 MAZZARI DARREL A
  • US8399262B2 patent drawing
  • US8399262B2 patent drawing
  • US8399262B2 patent drawing

AI summary

Disclosed herein are biosensors for the detection of airborne biomolecules. The biosensors include a housing, a sensing component, and optionally a sample capture component. The biosensors may utilize a gel-based detection platform.