Gel Hand Sanitizer Formulation for Stability, Moisture, and Virus Killing

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Solution Overview

Problem

Existing gel hand sanitizers lack good stability, moisture retention, and effective killing effects on common fungi and viruses, particularly Candida albicans and polioviruses.

Innovation Solution

A gel hand sanitizer composition comprising 75-85 wt % monohydric alcohol, 0.05-1 wt % hydrogen peroxide, 0.1-2 wt % thickener, and 0.01-1 wt % neutralizer, with the neutralizer having a structure represented by CaHbNcOd (a≥6, b≥15, 1≤c<3, and 1≤d<6), along with optional additives like caprylyl glycol and moisturizers, to enhance stability and killing effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If conventional gel hand sanitizer formulations are used, then the product provides basic cleaning effects, but the stability and moisture retention properties are insufficient

Engineering Contradiction:
ImprovestabilityVSAvoidmoisture retention
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent optimizes the concentration parameters of key ingredients: monohydric alcohol (75-85 wt%), hydrogen peroxide (0.05-1 wt%), and thickener (0.1-2 wt%). By precisely controlling these parameter ranges, the formulation achieves both improved stability and moisture retention properties simultaneously

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite gel formulation by combining multiple functional ingredients: monohydric alcohol for disinfection, hydrogen peroxide for enhanced antimicrobial activity, thickener for gel structure, and neutralizer for pH balance. This composite approach resolves the contradiction by synergistically improving both stability and moisture retention

Inventive Principle:
Principle #40Composite materials

2Ease of manufacture

If conventional gel hand sanitizer formulations are used, then the product is easy to manufacture, but the killing effects on fungi and viruses are insufficient

Engineering Contradiction:
Improveease of manufactureVSAvoidfungi and virus killing effects
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The patent incorporates hydrogen peroxide (0.05-1 wt%) as a strong oxidizing agent that enhances the killing effects on fungi and viruses. This maintains ease of manufacture since hydrogen peroxide is a stable, readily available ingredient that can be simply mixed into the gel formulation without complex processing

Inventive Principle:
Principle #38Strong oxidants (Accelerated oxidation)

Solution Approach 2:

The monohydric alcohol component serves multiple functions: it acts as the primary disinfectant, provides gel formation, and facilitates penetration of other active ingredients. This multi-functionality enhances fungi and virus killing effects while maintaining simple manufacturing processes

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Object-affected harmful factors

If the concentration of active ingredients is increased to improve killing effects, then the fungi and virus killing effects are enhanced, but the stability of the formulation deteriorates

Engineering Contradiction:
Improvefungi and virus killing effectsVSAvoidstability
Core Design Contradiction:
Object-affected harmful factorsVSStability of the object's composition

Solution Approach 1:

The patent identifies optimal concentration ranges that balance killing efficacy and stability: monohydric alcohol at 75-85 wt% provides sufficient antimicrobial activity while maintaining formulation stability; hydrogen peroxide at 0.05-1 wt% enhances killing effects without causing excessive instability. These parameter optimizations resolve the contradiction between potency and stability

Inventive Principle:
Principle #35Parameter changes

4Stability of the object's composition

If thickener is added to improve gel stability, then the viscosity and gel structure are improved, but the moisture retention properties worsen

Engineering Contradiction:
Improvegel structureVSAvoidmoisture retention
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent optimizes the thickener concentration to 0.1-2 wt%, which is sufficient to provide stable gel structure and appropriate viscosity but not so high as to excessively reduce moisture retention. This parameter optimization resolves the contradiction between gel stability and moisture retention

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The formulation achieves good stability, moisture retention, and excellent killing effects on both fungi and viruses, forming a stable gel system with improved viscosity.

Implementation Method 1

0.05-1 wt % of hydrogen peroxide

Methodology Applied
Scientific EffectOxidation: Oxidation

Implementation Method 2

75-85 wt % of a monohydric alcohol

Methodology Applied
Scientific EffectDenaturation:

Implementation Method 3

0.1-2 wt % of a thickener

Methodology Applied
Scientific EffectViscosity enhancement:

Data Source

PatentUS20250213440A1Gel hand sanitizer and preparation method therefor
Publication Date: 2025.07.03 SOLVENTUM INTELLECTUAL PROPERTIES CO
  • US20250213440A1 patent drawing

AI summary

Provided in the present invention are a gel hand sanitizer and a method for preparing a gel hand sanitizer. The gel hand sanitizer comprises, based on the total weight thereof: 75-85 wt % of a monohydric alcohol; 0.05-1 wt % of hydrogen peroxide; 0.1-2 wt % of a thickener; 0.01-1 wt % of a neutralizer; and the balance of water. The neutralizer has a structure represented by the general formula: CaHbNcOd, where a≥6, b≥15, 1≤c&lt;3, and 1≤d&lt;6. According to the technical solution of the present invention, a gel hand sanitizer with good stability, moisture retention, and good fungi and virus killing effects can be provided.