Bone Growth Delivery via Gelatinizable Syringe

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Solution Overview

Problem

Current methods for delivering bone growth promoting materials in dental applications often result in inadvertent spillage and improper placement, leading to inefficient bone augmentation due to the slow growth of bone tissue and subsequent atrophy of jaw bone after tooth removal.

Innovation Solution

A delivery system utilizing a water-absorbing gelatinizable material to encase bone growth promoting materials, which can be configured in various shapes and sizes, and delivered via a syringe as a paste or gel, ensuring precise placement and adhesion to the bone defect, while optionally using a polymerizable resin barrier to prevent soft tissue intrusion.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If bone growth promoting materials are manually delivered using a spatula or spoon, then the materials can be placed into the bone defect, but inadvertent spillage and placement into unintended locations occurs

Engineering Contradiction:
Improveplacement precisionVSAvoidmaterial spillage
Core Design Contradiction:
Manufacturing precisionVSLoss of substance

Solution Approach 1:

The bone growth promoting material is pre-loaded into a syringe device before the procedure, allowing the practitioner to control delivery precisely. The syringe is prepared in advance with the material, eliminating the need for manual transfer from spoons or spatulas and preventing spillage during the loading process.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

A syringe acts as an intermediary delivery device between the bone growth promoting material and the bone defect. This intermediary tool provides controlled dispensing through a needle or tip, enabling precise placement into the intended location while preventing accidental spillage that occurs with direct manual application.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Stability of the object's composition

If bone growth promoting granules are pre-mixed with blood to cause adhesion, then the material adheres together, but the ability to form the material to fill the augmentation site as intended is lost

Engineering Contradiction:
Improvematerial adhesionVSAvoidsite filling precision
Core Design Contradiction:
Stability of the object's compositionVSManufacturing precision

Solution Approach 1:

The blood-mixing step is extracted or eliminated from the procedure. Instead of requiring the practitioner to mix granules with blood at the site, the material is pre-formulated or delivered in a form that provides adhesion without requiring blood mixing, thereby maintaining both adhesion and precise site-filling capability.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The physical or chemical parameters of the bone growth promoting material are modified to provide inherent adhesion properties without requiring blood mixing. This could involve using materials with surface treatments, adhesive coatings, or formulations that bond to bone tissue directly, eliminating the need for blood as an adhesive agent.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If granular bone substitutes are delivered manually, then the materials can be placed in the defect, but control over material placement and distribution is poor

Engineering Contradiction:
Improvedelivery simplicityVSAvoidmaterial distribution control
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

A syringe serves as an intermediary delivery device that combines ease of operation with precise control. The syringe is simple to use (pulled back on the plunger) yet provides excellent control over material distribution through its needle or tip, allowing the practitioner to direct the material exactly where needed in the bone defect.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The material is pre-loaded into the syringe in the desired amount and configuration before the procedure. This preliminary preparation ensures that the material is ready for controlled delivery, allowing the practitioner to simply operate the syringe without worrying about measuring or transferring materials, thereby achieving both ease of operation and precise distribution control.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively promotes bone growth by physically excluding soft tissue and forming a matrix for bone integration, enhancing the structural integrity of the jaw bone by preventing atrophy and fracture, particularly in areas like the alveolar ridge.

Implementation Method 1

a water-absorbing gelatinizable material to encase bone growth promoting materials

Methodology Applied
Scientific EffectWater absorption: Absorption (physical)

Implementation Method 2

water-absorbing gelatinizable material

Methodology Applied
Scientific EffectGelatinization: Gel

Implementation Method 3

optionally using a polymerizable resin barrier to prevent soft tissue intrusion

Methodology Applied
Scientific EffectPolymerization: Photopolymerisation

Data Source

PatentUS8277828B2Delivery system for bone growth promoting material
Publication Date: 2012.10.02 ULTRADENT PROD INC
  • US8277828B2 patent drawing
  • US8277828B2 patent drawing
  • US8277828B2 patent drawing

AI summary

A delivery system that includes a bone growth promoting material encapsulated within a water absorptive gelatinizable covering is used to promote bone growth in order to repair a bone defect and/or strengthen a weakened bone region. The delivery system may be shaped and sized in order to fit within a bleeding wound (e.g. one that is formed in the gingiva when a tooth is extracted). The covering may be formed of a gelatinizable gauze that forms a gel-like material when moistened with water. The delivery system is contained within a moisture resistant package prior to use. Alternatively, the delivery system comprises a bone growth promoting material and thickening agent contained within a syringe that, upon adding water, form a viscous gel or stiff putty. A polymerizable resin may be placed over the bone growth composition after placement on a bone to form a protective barrier layer.