Bone Growth Delivery via Gelatinizable Syringe
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Solution Overview
Problem
Current methods for delivering bone growth promoting materials in dental applications often result in inadvertent spillage and improper placement, leading to inefficient bone augmentation due to the slow growth of bone tissue and subsequent atrophy of jaw bone after tooth removal.
Innovation Solution
A delivery system utilizing a water-absorbing gelatinizable material to encase bone growth promoting materials, which can be configured in various shapes and sizes, and delivered via a syringe as a paste or gel, ensuring precise placement and adhesion to the bone defect, while optionally using a polymerizable resin barrier to prevent soft tissue intrusion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If bone growth promoting materials are manually delivered using a spatula or spoon, then the materials can be placed into the bone defect, but inadvertent spillage and placement into unintended locations occurs
Solution Approach 1:
The bone growth promoting material is pre-loaded into a syringe device before the procedure, allowing the practitioner to control delivery precisely. The syringe is prepared in advance with the material, eliminating the need for manual transfer from spoons or spatulas and preventing spillage during the loading process.
Solution Approach 2:
A syringe acts as an intermediary delivery device between the bone growth promoting material and the bone defect. This intermediary tool provides controlled dispensing through a needle or tip, enabling precise placement into the intended location while preventing accidental spillage that occurs with direct manual application.
2Stability of the object's composition
If bone growth promoting granules are pre-mixed with blood to cause adhesion, then the material adheres together, but the ability to form the material to fill the augmentation site as intended is lost
Solution Approach 1:
The blood-mixing step is extracted or eliminated from the procedure. Instead of requiring the practitioner to mix granules with blood at the site, the material is pre-formulated or delivered in a form that provides adhesion without requiring blood mixing, thereby maintaining both adhesion and precise site-filling capability.
Solution Approach 2:
The physical or chemical parameters of the bone growth promoting material are modified to provide inherent adhesion properties without requiring blood mixing. This could involve using materials with surface treatments, adhesive coatings, or formulations that bond to bone tissue directly, eliminating the need for blood as an adhesive agent.
3Ease of operation
If granular bone substitutes are delivered manually, then the materials can be placed in the defect, but control over material placement and distribution is poor
Solution Approach 1:
A syringe serves as an intermediary delivery device that combines ease of operation with precise control. The syringe is simple to use (pulled back on the plunger) yet provides excellent control over material distribution through its needle or tip, allowing the practitioner to direct the material exactly where needed in the bone defect.
Solution Approach 2:
The material is pre-loaded into the syringe in the desired amount and configuration before the procedure. This preliminary preparation ensures that the material is ready for controlled delivery, allowing the practitioner to simply operate the syringe without worrying about measuring or transferring materials, thereby achieving both ease of operation and precise distribution control.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively promotes bone growth by physically excluding soft tissue and forming a matrix for bone integration, enhancing the structural integrity of the jaw bone by preventing atrophy and fracture, particularly in areas like the alveolar ridge.
Implementation Method 1
a water-absorbing gelatinizable material to encase bone growth promoting materials
Implementation Method 2
water-absorbing gelatinizable material
Implementation Method 3
optionally using a polymerizable resin barrier to prevent soft tissue intrusion
Data Source
AI summary
A delivery system that includes a bone growth promoting material encapsulated within a water absorptive gelatinizable covering is used to promote bone growth in order to repair a bone defect and/or strengthen a weakened bone region. The delivery system may be shaped and sized in order to fit within a bleeding wound (e.g. one that is formed in the gingiva when a tooth is extracted). The covering may be formed of a gelatinizable gauze that forms a gel-like material when moistened with water. The delivery system is contained within a moisture resistant package prior to use. Alternatively, the delivery system comprises a bone growth promoting material and thickening agent contained within a syringe that, upon adding water, form a viscous gel or stiff putty. A polymerizable resin may be placed over the bone growth composition after placement on a bone to form a protective barrier layer.


