Gelled Emulsion Veterinary Composition for Palatable Drug Delivery
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Solution Overview
Problem
Domestic animals, especially carnivorous pets like dogs and cats, often refuse to consume oral veterinary tablets due to their texture and taste, and they frequently suffer from lipid and vitamin malnutrition associated with conditions like exocrine pancreatic insufficiency, which impairs fat and fat-soluble vitamin uptake.
Innovation Solution
A physiologically tolerable gelled oil-in-water emulsion for oral administration, enhanced with animal flavorings like chicken, beef, pork, lamb, or fish, which increases the attractiveness and bioavailability of veterinary drugs and nutritional supplements, including lipids, vitamins, and digestive enzymes, by dispersing the drug in the water phase and using omega-3 rich oils to improve nutrient uptake.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If oral veterinary tablets are presented in conventional tablet form, then the medication can be administered orally, but animals refuse to consume them due to texture and taste
Solution Approach 1:
The patent changes the physical state and sensory properties of the medication by transforming it from a solid tablet into a gelled emulsion with controlled texture, viscosity, and flavor characteristics that match animal preferences, thereby eliminating consumption avoidance while maintaining oral administration capability
Solution Approach 2:
The gelled emulsion acts as an intermediary carrier that bridges the gap between the medicinal substance and the animal's palatable preferences, using flavorings and texture modifiers as intermediaries to make the medication acceptable to animals
2Ease of manufacture
If lipid-filled capsules are used for nutritional supplementation, then the composition is easy to manufacture, but uptake of lipid nutrients is lower
Solution Approach 1:
The patent changes the physical state of lipid nutrients from encapsulated solid/liquid form to a gelled emulsion state, which fundamentally alters their bioavailability and uptake efficiency in the animal gastrointestinal tract
Solution Approach 2:
The invention creates a composite gelled emulsion system combining lipid nutrients, water-soluble vitamins, minerals, and gelling agents in a unified formulation that enhances the bioavailability and absorption of all nutrients simultaneously
3Reliability
If exocrine pancreatic insufficiency is present, then fat and fat-soluble vitamin uptake is impaired, but the condition requires nutritional supplementation
Solution Approach 1:
The patent modifies the physical and chemical parameters of the nutritional supplementation by using a gelled emulsion formulation with specific viscosity, fat content, and gelling agent composition that enhances absorption in animals with impaired pancreatic function
Solution Approach 2:
The gelled emulsion acts as an intermediary that facilitates nutrient absorption in animals with EPI by providing a controlled release mechanism and enhancing lipid emulsification in the gastrointestinal tract, compensating for pancreatic insufficiency
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The gelled emulsion formulation significantly enhances the consumption and absorption of lipid nutrients, reduces avoidance of the medication, and effectively treats conditions responsive to the veterinary drugs, providing a more palatable and effective treatment method for non-human mammals.
Implementation Method 1
a physiologically tolerable gelled oil-in-water emulsion further comprising an attractant which is a chicken, beef, pork, lamb, rabbit or fish flavouring, and a veterinary drug, wherein the veterinary drug is dispersed in the water phase of the emulsion
Implementation Method 2
a physiologically tolerable gelled oil-in-water emulsion
Data Source
AI summary
This invention provides an oral veterinary pharmaceutical or nutraceutical composition comprising a physiologically tolerable gelled oil-in-water emulsion further comprising at least one component selected from taste enhancers, odour enhancers, digestive enzymes and veterinary drugs.