GelMA Capacitive Tactile Sensor for Wearable Biosensing

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current wearable pressure sensors face challenges such as mechanical mismatch with human tissue, biocompatibility issues, water evaporation, and lack of cost-effective fabrication techniques, limiting their practical applications for long-term monitoring of physiological signals.

Innovation Solution

A GelMA-based capacitive tactile sensor is developed with a layer-by-layer stacked structure using PDMS/GelMA/PDMS as dielectric layers and PEDOT:PSS as electrodes, which enhances mechanical and electrical properties, prevents water evaporation, and improves interface bonding, resulting in a highly sensitive and durable pressure sensor.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If hydrogels are used as dielectric layers in wearable pressure sensors, then biocompatibility and mechanical matching with human tissue are improved, but water evaporation occurs leading to performance degradation

Engineering Contradiction:
ImprovebiocompatibilityVSAvoidwater evaporation
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

A PDMS encapsulation layer is introduced as an intermediary between the GelMA hydrogel dielectric layer and the external environment. This PDMS layer acts as a barrier that prevents water evaporation from the hydrogel while allowing the hydrogel to maintain its biocompatibility and mechanical properties for sensing applications.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If hydrogel-based pressure sensors are developed, then sensitivity to physiological signals is improved, but interface bonding strength between sensor layers is weakened

Engineering Contradiction:
Improvepressure sensitivityVSAvoidinterface bonding
Core Design Contradiction:
Measurement precisionVSStrength

Solution Approach 1:

The PDMS encapsulation layer serves as a bonding intermediary that chemically or physically adheres to both the GelMA hydrogel dielectric layer and other sensor components (electrodes, substrates). This intermediary layer strengthens the interface bonding while allowing the hydrogel to maintain its sensitivity for detecting physiological pressure signals.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Ease of manufacture

If conventional fabrication techniques are used for wearable sensors, then manufacturing process is simplified, but cost-effectiveness and scalability for large-scale production are reduced

Engineering Contradiction:
Improvefabrication simplicityVSAvoidlarge-scale production efficiency
Core Design Contradiction:
Ease of manufactureVSProductivity

Solution Approach 1:

The patent employs solution processing techniques where sensor components are fabricated by depositing materials from liquid solutions followed by controlled drying or curing processes. This approach maintains fabrication simplicity while enabling scalable large-scale production through techniques like spin-coating, dip-coating, or spray deposition that can be easily automated and scaled up.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The GelMA-based sensor demonstrates improved sensitivity, durability, and long-term stability, with a lower limit of detection and higher sensitivity compared to previous hydrogel-based sensors, suitable for monitoring human physiological signals like pulse and vocal cord vibration.

Implementation Method 1

GelMA hydrogel was used as a dielectric layer in an electrical capacitor

Methodology Applied
Scientific EffectDielectric: Dielectric

Implementation Method 2

the electrical property (e.g., dielectric constant) of GelMA hydrogels was investigated

Methodology Applied
Scientific EffectCapacitance: Capacitance

Implementation Method 3

A wearable piezoresistive pressure sensor with pressure sensitivity of 0.05 kPa−1 using a PVA-polyacrylamide (PAAm) hydrogel has also been demonstrated

Methodology Applied
Scientific EffectHydrogel: Hydrogel

Implementation Method 4

the conducting polymer PEDOT:PSS used as transparent electrodes

Methodology Applied
Scientific EffectElectrical Conductivity: Conduction (electrical)

Data Source

PatentUS20230277080A1SOFT BIOSENSORS BASED ON GELATIN METHACRYLOYL (GelMA)
Publication Date: 2023.09.07 RGT UNIV OF CALIFORNIA
  • US20230277080A1 patent drawing
  • US20230277080A1 patent drawing
  • US20230277080A1 patent drawing

AI summary

A gelatin methacryloyl (GelMA)-based biosensor device for wearable biosensing applications is disclosed. An exemplary capacitive tactile sensor with GelMA used as the core dielectric layer is disclosed. A robust chemical bonding and a reliable encapsulation approach are introduced to overcome detachment and water-evaporation issues in hydrogel biosensors. The resultant GelMA tactile sensor shows a high-pressure sensitivity of 0.19 kPa−1 and one order of magnitude lower limit of detection (0.1 Pa) compared to previous hydrogel pressure sensors owing to its excellent mechanical and electrical properties (e.g., dielectric constant). Furthermore, it shows durability up to 3,000 test cycles because of tough chemical bonding, and long-term stability of three (3) days due to the inclusion of an encapsulation layer, which prevents water evaporation (e.g., 80% water content). Successful monitoring of various human physiological and motion signals demonstrates the potential of the GelMA biosensor device for wearable biosensing applications.