Generative Metabolic Prediction Models Using Continuous Glucose Data

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current healthcare systems face challenges in providing continuous data for metabolic values, leading to limited treatment options and recommendations based on sporadic readings, particularly in managing chronic conditions like diabetes, which often rely on isolated glucose measurements.

Innovation Solution

A computer-implemented method using a generative machine learning model trained with continuous glucose monitoring data to predict metabolic values, incorporating glycemia risk index and time in range metrics, and historical data to generate actionable insights and recommendations.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If sporadic glucose readings are used for diabetes treatment, then device complexity is reduced, but measurement precision and reliability of treatment decisions deteriorate

Engineering Contradiction:
Improvemonitoring system complexityVSAvoidglucose level prediction accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent implements continuous glucose monitoring that collects glucose level data continuously over time rather than relying on sporadic readings. This continuous data collection enables the machine learning model to learn patterns and generate accurate predictions, resolving the contradiction by maintaining continuous monitoring action without requiring complex intervention at each measurement point.

Inventive Principle:
Principle #20Continuity of useful action

Solution Approach 2:

The system performs preliminary data collection and model training in advance by accumulating historical glucose data and training the machine learning model beforehand. This preliminary action enables accurate predictions to be generated when needed, improving measurement precision without requiring complex real-time processing during critical decision moments.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If continuous glucose monitoring data is collected and processed, then prediction accuracy improves, but loss of time for data processing and model training increases

Engineering Contradiction:
Improvemetabolic value prediction accuracyVSAvoiddata processing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The patent performs model training in advance using historical data before predictions are needed. By completing the computationally intensive training process beforehand, the system minimizes data processing time during actual prediction scenarios while maintaining high accuracy through the trained model's ability to quickly generate predictions from continuous monitoring data.

Inventive Principle:
Principle #10Preliminary action

3Reliability

If more historical metabolic data is used for training, then model reliability improves, but quantity of data to be processed increases

Engineering Contradiction:
Improveprediction model reliabilityVSAvoidvolume of training data
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent extracts and utilizes specifically relevant features from the historical metabolic data such as glucose levels, insulin doses, carbohydrate intake, and exercise information. By selecting and extracting only the most pertinent features rather than processing all raw data, the system achieves high model reliability with reduced data processing requirements.

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS20250303064A1Systems and methods for metabolic outcome predictions
Publication Date: 2025.10.02 WELLDOC INC
  • US20250303064A1 patent drawing
  • US20250303064A1 patent drawing
  • US20250303064A1 patent drawing

AI summary

A method may receive historical metabolic values for an individual having a first medical condition. A method may provide a first subset of the historical metabolic values to a machine learning model to train a generative machine learning model. A method may generate a first predicted metabolic value based on the first subset of historical metabolic values. A method may calculate a root mean square error (RMSE) between the first predicted metabolic value and a corresponding actual metabolic value of a second subset of historical metabolic values. A method may train the generative machine learning model to minimize the RMSE. A method may generate a trained generative machine learning model based on the training.