Genetic Nutrition Mapping for Personalized IV and IM Therapy
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Solution Overview
Problem
Current IV and IM nutrition therapies use generic formulations that do not account for individual nutritional needs, leading to suboptimal supplementation and less effective therapy due to excess or missing nutrients.
Innovation Solution
A method of providing genetically personalized IV and IM nutrition therapy by mapping micronutrients to SNPs, symptoms, and therapeutic objectives based on existing scientific literature, updating this mapping with patient feedback to create a personalized treatment formula.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Adaptability or versatility
If generic formulations are used for IV and IM nutrition therapy, then the therapy can be applied universally to all patients, but the therapy effectiveness decreases because it does not account for individual nutritional needs
Solution Approach 1:
The patent applies local quality by customizing the nutritional formulation for each patient based on their genetic profile (SNPs), symptoms, and therapeutic objectives. Instead of using a uniform generic formulation for all patients, the system creates locally optimized formulations that address individual nutritional needs, thereby maintaining universality of application while improving therapy effectiveness through personalization.
2Ease of manufacture
If generic formulations are used for IV and IM nutrition therapy, then the formulation process is simple and quick, but the nutrient balance is incorrect leading to excess or missing nutrients
Solution Approach 1:
The patent applies preliminary action by pre-establishing a comprehensive database that maps micronutrients to SNPs, symptoms, and therapeutic objectives based on existing scientific literature. This preliminary mapping allows the system to quickly retrieve and assemble personalized formulations without requiring complex real-time analysis, thus maintaining ease of manufacture while achieving high manufacturing precision in nutrient balance.
3Reliability
If individualized nutrition therapy is designed based on genetic data and patient feedback, then the therapy effectiveness improves, but the system complexity increases due to continuous learning and mapping updates
Solution Approach 1:
The patent applies self-service by implementing an automated feedback loop where patient treatment outcomes automatically update the micronutrient mapping database. The system self-updates and refines its personalized formulations based on accumulated patient data without requiring manual intervention, thereby improving therapy effectiveness while managing system complexity through automation rather than manual processes.
Data Source
AI summary
A method of providing genetically personalized intravenous or intramuscular nutrition therapy includes developing an initial mapping of individual micronutrients to SNPs, symptoms, conditions, and therapeutic objectives based on existing individual scientific literature references that link the specific micronutrient to an SNP, a symptom, a condition, or a therapeutic objective. The method includes receiving an SNP and a symptom, a condition, or a therapeutic objective for a patient, comparing the SNP, symptom, condition, therapeutic objective combination with the initial mapping to identify matching micronutrients, determining a nutrition therapy based on the identified micronutrients, and treating the patient accordingly. Feedback data about the nutrition therapy's effectiveness is received and the initial mapping is updated to account for the feedback data. This process is repeated for subsequent patients positioned geographically remotely from each other so that future patients are treated with reference to an updated current mapping.