Genetic Testing Tip Set with Piercing and Injection Mechanisms

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Solution Overview

Problem

The existing genetic testing devices face contamination issues due to sample solution adhesion to the pipette head during the injection process, leading to cross-contamination of different sample solutions.

Innovation Solution

A tip set comprising a piercing tip and an injection tip, where the piercing tip is connected to the injection tip via a fitting portion, preventing direct contact between the injection tip and the pipette head and blocking the opening to prevent sample solution leakage, while an air vent reduces internal pressure and facilitates precise sample injection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Device complexity

If the injection tip is mounted directly on the pipette head, then the device structure is simple, but the sample solution adheres to the pipette head causing contamination

Engineering Contradiction:
Improvedevice structureVSAvoidsample solution contamination
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The piercing tip serves as an intermediary component between the injection tip and the pipette head. The piercing tip connects to the injection tip while its other end interfaces with the pipette head, preventing direct contact between the injection tip and pipette head. This intermediary structure eliminates the adhesion problem while maintaining operational simplicity.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If the opening of the reservoir is blocked to prevent leakage, then sample solution contamination is prevented, but internal pressure builds up affecting injection accuracy

Engineering Contradiction:
Improvesample solution leakageVSAvoidinjection accuracy
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The piercing tip features a localized opening at its tip portion that is distinct from the main reservoir opening. This local opening allows controlled pressure release specifically at the injection interface while the main reservoir opening remains blocked to prevent leakage. The differentiated opening structures address both leakage prevention and pressure control requirements.

Inventive Principle:
Principle #3Local quality

3Reliability

If the piercing tip inserts deep into the reservoir to block the opening, then leakage is prevented, but the fitting becomes unstable

Engineering Contradiction:
Improvesample solution leakageVSAvoidfitting stability
Core Design Contradiction:
ReliabilityVSStability of the object's composition

Solution Approach 1:

The piercing tip is divided into functionally distinct segments: a tip portion with a small opening for pressure control, a middle portion with the fitting structure, and a base portion for connection. This segmentation allows the tip to insert to an appropriate depth for leakage prevention while maintaining a stable fitting through the differentiated structural zones.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The piercing tip employs asymmetric geometry with a tapered tip portion that inserts into the reservoir opening, followed by a wider middle portion that provides a stable fitting base. This asymmetric shape enables deep insertion for leakage prevention while the wider base ensures stable connection, resolving the contradiction between insertion depth and fitting stability.

Inventive Principle:
Principle #4Asymmetry

Data Source

PatentEP3719504B1Tip set
Publication Date: 2024.07.03 EIKEN KAGAKU
  • EP3719504B1 patent drawingFigure 1
  • EP3719504B1 patent drawingFigure 2
  • EP3719504B1 patent drawingFigure 3

AI summary

Provided is a tip set used for a genetic testing device. The tip set includes a piercing tip breaking a lid portion of a reagent container filled with a reagent to open the reagent container and an injection tip injecting a sample solution containing a target gene nucleic acid into a microchip. The injection tip has a reservoir storing the sample solution in an internal space and an injection needle protruding from the reservoir, an opening opening the internal space to a side opposite to the injection needle is formed in the reservoir, and the piercing tip has a fitting portion fitted to the injection tip to connect the injection tip and the piercing tip.