Selective Geniposide Removal via Activated Carbon Adsorption

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Solution Overview

Problem

Current methods are ineffective in removing geniposide and genipin from gardenia-derived colorants, leading to potential toxicity and skin discoloration issues, with existing techniques like activated carbon treatment failing to selectively remove these compounds without affecting the colorant components.

Innovation Solution

Using an activated carbon with specific adsorption abilities, such as a methylene blue adsorption capacity of 50 ml/g or more and iodine adsorption ability of 750 mg/g or more, to selectively remove geniposide and genipin from gardenia-derived colorants while preserving the colorant components.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If activated carbon treatment is used to remove geniposide and genipin, then the harmful substances are reduced, but the colorant components are also adsorbed and lost

Engineering Contradiction:
Improvegeniposide and genipin contentVSAvoidcolorant component loss
Core Design Contradiction:
Object-affected harmful factorsVSLoss of substance

Solution Approach 1:

The patent applies local quality by specifying particular properties for the activated carbon (iodine adsorption ability ≥750 mg/g, methylene blue adsorption ability ≥50 ml/g) to create selective adsorption. This targeted approach allows the activated carbon to preferentially adsorb geniposide and genipin while minimizing adsorption of colorant components, resolving the contradiction between removing harmful substances and preserving useful substances.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs parameter changes by adjusting the adsorption characteristics of activated carbon through selection of specific materials with defined adsorption capacities. By changing the parameters of the activated carbon (iodine adsorption ability, methylene blue adsorption ability), the process achieves selective removal of geniposide and genipin without significant loss of colorant components.

Inventive Principle:
Principle #35Parameter changes

2Ease of manufacture

If conventional activated carbon is used for purification, then the purification process is simple, but the removal of geniposide and genipin is ineffective

Engineering Contradiction:
Improvepurification process simplicityVSAvoidgeniposide and genipin removal efficiency
Core Design Contradiction:
Ease of manufactureVSManufacturing precision

Solution Approach 1:

The patent maintains the simplicity of the activated carbon treatment process while improving removal efficiency by changing the parameters of the activated carbon itself. By selecting activated carbon with specific adsorption abilities (iodine ≥750 mg/g, methylene blue ≥50 ml/g), the process achieves effective geniposide and genipin removal without complicating the manufacturing procedure.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent uses activated carbon that replicates or exceeds the adsorption capabilities of conventional activated carbon while adding selective removal properties. The specified adsorption abilities create a enhanced version of conventional activated carbon that maintains ease of use while achieving superior purification precision.

Inventive Principle:
Principle #26Copying

3Object-affected harmful factors

If more activated carbon is used to increase geniposide and genipin removal, then the harmful substance removal improves, but the cost and complexity increase

Engineering Contradiction:
Improvegeniposide and genipin contentVSAvoidpurification process complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The patent applies local quality by specifying particular properties for the activated carbon (iodine adsorption ability ≥750 mg/g, methylene blue adsorption ability ≥50 ml/g) to create selective adsorption. This targeted approach allows the activated carbon to preferentially adsorb geniposide and genipin while minimizing adsorption of colorant components, resolving the contradiction between removing harmful substances and preserving useful substances.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent employs parameter changes by adjusting the adsorption characteristics of activated carbon through selection of specific materials with defined adsorption capacities. By changing the parameters of the activated carbon (iodine adsorption ability, methylene blue adsorption ability), the process achieves selective removal of geniposide and genipin without significant loss of colorant components.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method effectively reduces the total content of geniposide and genipin in gardenia-derived colorants, minimizing toxicity risks and skin discoloration while maintaining the colorant's effectiveness, as demonstrated by the use of activated carbon No. 7 and No. 8 in the provided examples.

Implementation Method 1

treating a gardenia-derived colorant containing geniposide or genipin or both using an activated carbon having: (a) a methylene blue adsorption ability, as determined according to JIS K 1474:2014, of 50 ml/g or more; and (b) an iodine adsorption ability, as determined according to JIS K 1474:2014, of 750 mg/g or more, thereby removing geniposide or genipin or both

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentEP3222681B1Method for removing geniposide or genipin or both
Publication Date: 2023.06.28 SAN EI GEN F F I INC
  • EP3222681B1 patent drawingFigure 1
  • EP3222681B1 patent drawingFigure 2
  • EP3222681B1 patent drawingFigure 3

AI summary

An object of the present invention is to provide a method for removing geniposide or genipin or both from a material containing geniposide or genipin or both. The present invention is a method for removing geniposide or genipin or both from a material containing geniposide or genipin or both, the method comprising treating the material containing geniposide or genipin or both using an activated carbon having (a) a methylene blue adsorption ability of 50 ml/g or more; and (b) an iodine adsorption ability of 750 mg/g or more, thereby removing geniposide or genipin or both.