Genome Browser Multi-Track Visualization
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Solution Overview
Problem
The analysis and representation of genome-related biological data are hindered by the vast amount of available data, including next-generation sequencing and microarray data, which often requires human interpretation and lacks efficient tools for data visualization and comparison.
Innovation Solution
A computer-implemented system and method for analyzing and representing genomic data, including generating graphical representations with multiple tracks for different organisms, determining syntenic regions, and reordering tracks based on genetic similarity, allowing for intuitive user interaction and data visualization.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If genome-related biological data is collected from multiple organisms using next generation sequencing and microarrays, then the quantity and comprehensiveness of data is improved, but the complexity of data analysis and visualization increases
Solution Approach 1:
The patent segments the complex genomic data by organizing it into multiple separate tracks, each representing a different organism or data type. This allows the system to handle large quantities of data from multiple organisms without overwhelming the user interface, as each track can be independently managed and visualized.
Solution Approach 2:
The patent adds a dimensional organization to genomic data visualization by arranging data from multiple organisms in a multi-track layout. This transforms the complex multidimensional data structure into a visually manageable format where each organism's data occupies a separate dimensional space (track), making comparison and analysis more efficient.
2Adaptability or versatility
If genomic data from multiple organisms is displayed simultaneously, then the ability to compare and identify genetic associations is improved, but the clarity and interpretability of the visualization deteriorates
Solution Approach 1:
The patent segments the visualization into distinct tracks for different organisms, allowing simultaneous display while maintaining clarity. Each track is separated and organized, enabling users to compare genomic features across organisms without the visual complexity overwhelming the interpretation.
Solution Approach 2:
The patent allows users to selectively focus on specific tracks or regions of interest rather than requiring interpretation of all data simultaneously. Users can examine individual organism data in detail or compare specific features across organisms, applying partial attention to manageable subsets of the full dataset.
3Adaptability or versatility
If tracks are arranged to show features of multiple organisms, then the comprehensiveness of genomic analysis is improved, but the time required to process and display the data increases
Solution Approach 1:
The patent performs preliminary organization of genomic data into track structures before full visualization is required. Data from multiple organisms is pre-segmented and arranged in the multi-track layout, so that when the user requests comprehensive analysis, the data is already structured and ready for efficient display without requiring real-time processing of all organism data.
Data Source
AI summary
This document describes, among other things, a computer-implemented method for displaying and analyzing sequenced genome data. The method can include obtaining, at a computing system, genomic data for a plurality of organisms. A graphical representation can of the genomic data can be generated by the computing system based at least on the genomic data for the plurality of organisms, and the graphical representation can include a plurality of tracks that are arranged to show one or more features of the genomic data for different ones of the plurality of organisms. The graphical representation can be output for display by the computing system.