Selective Genome Decryption GUI for Secure Disease Ranking

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Solution Overview

Problem

Existing human genome analysis tools lack real-time graphical user interface (GUI) management capabilities for target subjects or their representatives, providing unrestricted access to genomic data without adequate security measures.

Innovation Solution

A computer-implementable system with a GUI that manages genetic information by encrypting genomes, allowing real-time analysis and selective decryption of accessible data while blocking access to confidential data, using a system controller and database to rank genetic diseases based on phenotypic and genetic variants, and control user input commands.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If genomic data is provided with unrestricted access to clinicians and third party users, then ease of operation is improved, but security and privacy protection deteriorate

Engineering Contradiction:
Improveaccess to genomic dataVSAvoidsecurity measures
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent segments genomic data into accessible and confidential portions, allowing different levels of access control. The system divides the genome data structure to enable selective decryption and access management, resolving the contradiction between ease of access and security protection.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent implements local quality by applying different security attributes to different portions of genomic data. Accessible data portions are decrypted and made available for analysis, while confidential portions remain encrypted, allowing tailored access control based on data sensitivity.

Inventive Principle:
Principle #3Local quality

2Ease of operation

If real-time GUI management capabilities are implemented for target subjects or their representatives, then ease of operation is improved, but device complexity increases

Engineering Contradiction:
Improvereal-time GUI managementVSAvoidsystem architecture
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent introduces a monitoring controller as an intermediary component that manages access control and decryption operations. This mediator handles the complex security protocols and user authentication, simplifying the interface presented to end users while maintaining robust security controls.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system implements multi-functionality by integrating multiple capabilities into unified components. The monitoring controller performs authentication, access control, and decryption management functions, reducing overall system complexity despite the advanced features provided.

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Reliability

If selective decryption of genomic data portions is implemented, then reliability of security measures is improved, but loss of information increases

Engineering Contradiction:
Improvesecurity measuresVSAvoidaccess to confidential data
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The patent implements dynamic access control where the decryption state of genomic data portions can change based on user authorization and context. The system dynamically transitions data between encrypted and decrypted states, providing security when needed while allowing access when authorized, thus balancing security reliability with information availability.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS12525357B2System for managing genetic information associated with a human genome of a target subject and displayed via a graphical user interface (GUI)
Publication Date: 2026.01.13 TRAKADIS JOHN DR
  • US12525357B2 patent drawing
  • US12525357B2 patent drawing
  • US12525357B2 patent drawing

AI summary

A computer implementable system manages genetic information associated with a human genome of a target subject and displayed via a graphical user interface (GUI). The target subject genetic information is encrypted. The system compares the clinical data of the target subject with clinical data in its database to provide a first ranking of possible genetic diseases. Then the genetic information of the target subject is compared to the genetic information in the database to re-rank via a weight score evaluation based on predetermined criteria thereby providing a second ranking of possible genetic diseases. Allowing a user to decrypt a portion or portions of the encrypted target subject genome that are related to the possible genetic diseases and blocking decryption of the rest of the genome. Providing access to the decrypted portions of the target subject genome via the GUI.