Ginseng Ferment Composition for Immunity Without Hyperglycemia

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Solution Overview

Problem

Current immunological solutions fail to effectively enhance immunity in individuals, particularly those with sub-health issues and high blood sugar symptoms, while also avoiding the use of sweeteners like glucose and sucrose that can lead to hyperglycemia.

Innovation Solution

A ginseng ferment composition is created by mixing ginseng ethanol extract containing total saponins of Panax ginseng with a fruit and vegetable fermentation conversion solution, using a specific blend of bacteria and fermentation conditions to produce a pharmaceutical composition that enhances immunity, with the concentration of total saponins adjusted to 1.5g/l, 15g/l, or 50g/l.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If conventional immunological solutions are used to enhance immunity, then immune function may be improved, but they fail to effectively enhance immunity in individuals with sub-health issues and high blood sugar symptoms

Engineering Contradiction:
Improveimmunity enhancement effectivenessVSAvoidapplicability to different health conditions
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent modifies the chemical composition parameters by using ginseng ethanol extract containing total saponins instead of conventional immunological agents. This parameter change allows the composition to effectively enhance immunity in individuals with sub-health issues and high blood sugar symptoms, resolving the contradiction between effectiveness and adaptability to different health conditions.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent creates a composite pharmaceutical composition by combining ginseng ethanol extract with fruit and vegetable fermentation conversion solution. This composite material integrates the immune-enhancing properties of ginseng saponins with the beneficial effects of fermented vegetables and fruits, achieving broad-spectrum immunity enhancement suitable for various health conditions including sub-health states and high blood sugar symptoms.

Inventive Principle:
Principle #40Composite materials

2Ease of operation

If sweeteners like glucose and sucrose are used in immunological solutions, then palatability and acceptance are improved, but they lead to hyperglycemia in susceptible individuals

Engineering Contradiction:
Improvepalatability and acceptanceVSAvoidhyperglycemia risk
Core Design Contradiction:
Ease of operationVSObject-affected harmful factors

Solution Approach 1:

The patent extracts and eliminates harmful sweeteners (glucose and sucrose) from the immunological solution while retaining the beneficial immune-enhancing components. By removing these harmful substances, the composition avoids causing hyperglycemia in susceptible individuals while maintaining therapeutic effectiveness.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces conventional sweeteners with a fermentation-based sweetening system using fruit and vegetable fermentation conversion solution. This alternative sweetening approach provides necessary palatability without the harmful metabolic effects of glucose and sucrose, effectively substituting harmful substances with beneficial alternatives.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The ginseng ferment composition demonstrates improved extraction efficiency and effectiveness in enhancing immunity, as shown by experiments on immunocompromised individuals, with reduced usage of sweeteners like glucose and sucrose, benefiting a broader population.

Implementation Method 1

lactobacillus acidophilus bacteria solution, bifidobactreium longum bacteria solution, lactobacillus delbrueckiisubsp. bulgaricus bacteria solution, streptococcus thermophilus bacteria solution with water, and fermenting for obtaining the fermentation product

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

reflux extracting ginseng by ethanol aqueous solution for obtaining the extract, namely, the ginseng ethanol extract containing total saponins of panax ginseng

Methodology Applied
Scientific EffectReflux extraction: Liquid-Liquid Extraction

Data Source

PatentEP2676671B1Method for preparing pharmaceutical composition for enhancing immunity and pharmaceutical composition prepared according to the method
Publication Date: 2017.07.19 JILIN ZIXIN PHARMA RES INSTITUTION
  • EP2676671B1 patent drawing

AI summary

A method for preparing a pharmaceutical composition for enhancing immunity and a pharmaceutical composition prepared according to the method. The method includes steps of: mixing ginseng ethanol extract with fruit and vegetable fermentation conversion solution to obtain a mixture, namely, the pharmaceutical composition for enhancing immunity; wherein the ginseng ethanol extract is prepared by a following step of: reflux extracting ginseng by ethanol aqueous solution for obtaining the extract, namely, the ginseng ethanol extract; the fruit and vegetable fermentation conversion solution is prepared by following steps of: mixing fruit and vegetable, lactobacillus acidophilus bacteria solution, bifidobactreium longum bacteria solution, lactobacillus delbrueckiisubsp. bulgaricus bacteria solution, streptococcus thermophilus bacteria solution with water, and then fermenting for obtaining a fermentation product, namely, the fruit and vegetable fermentation conversion solution.