Ginseng Ginkgo Stigma Croci Composition for Cardiovascular Treatment

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Solution Overview

Problem

Current medicinal compositions for treating cardiovascular and cerebrovascular diseases and dementia, particularly vascular dementia, often require higher doses and may have significant side effects, with the effectiveness of soybean in these compositions being unclear.

Innovation Solution

A Chinese medicinal composition comprising a specific weight ratio of ginseng, ginkgo leaf, and stigma croci, optimized to reduce doses and side effects, with preferred ratios of 1 part ginseng to 0.8-1.5 parts ginkgo leaf and 0.018-0.030 parts stigma croci, prepared through various extraction methods to enhance pharmacological effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If higher doses of medicinal composition are used to treat cardiovascular and cerebrovascular diseases and dementia, then therapeutic efficacy is improved, but side effects increase

Engineering Contradiction:
Improvetherapeutic efficacyVSAvoidside effects
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent optimizes the weight ratios of ginseng (1 part), ginkgo leaf (0.8-1.5 parts), and stigma croci (0.018-0.030 parts) to achieve maximum therapeutic efficacy at reduced doses. This parameter optimization allows the composition to be effective at lower doses, thereby reducing side effects while maintaining treatment effectiveness for cardiovascular and cerebrovascular diseases and dementia

Inventive Principle:
Principle #35Parameter changes

2Adaptability or versatility

If soybean is included in the medicinal composition, then the composition is more complete, but the effectiveness of soybean is unclear and may add complexity

Engineering Contradiction:
Improvecomposition completenessVSAvoidingredient complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The patent removes soybean from the medicinal composition, retaining only ginseng, ginkgo leaf, and stigma croci. This extraction of the ineffective ingredient simplifies the composition while maintaining therapeutic efficacy, eliminating the uncertainty about soybean's contribution and reducing overall complexity

Inventive Principle:
Principle #2Taking out (Extraction)

Data Source

PatentUS10967023B2Preparation of a chinese medicinal composition including ginseng, ginkgo leaf and stigma croci
Publication Date: 2021.04.06 SHINEWAY PHARMA GRP LTD

AI summary

Disclosed is a Chinese medicinal composition prepared from the following medical raw materials in parts by weight: 1 part of ginseng, 0.8-1.5 parts of ginkgo leaf and 0.018-0.030 part of stigma croci.