Glaucoma Pump Implant Using Iris Dynamics for Active Pressure Reduction

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Solution Overview

Problem

Current glaucoma treatments rely on passive hydrostatic mechanisms for intraocular pressure reduction, which often lead to occlusion and inadequacy in reducing eye pressure due to clogging or halted drainage when pressure balances on both sides of the globe, lacking an active pumping mechanism to effectively manage intraocular fluid outflow.

Innovation Solution

The glaucoma pump implant utilizes the natural iris pump mechanism by harnessing the diameter changes of the pupil and iris to actively increase outflow through the trabecular meshwork, employing a flexible string to transmit tensile force and expand holes in the trabecular meshwork for unidirectional fluid flow, thereby reducing intraocular pressure without channel opening or clogging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If passive hydrostatic mechanism is used for intraocular pressure reduction, then surgical intervention is avoided, but occlusion occurs and drainage is halted when pressure balances on both sides of the globe

Engineering Contradiction:
Improveease of surgical interventionVSAvoidreliability of pressure reduction
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The implant transitions from a static passive structure to a dynamic active pump system that utilizes iris movements. The pump mechanism actively changes the volume of the trabecular meshwork through iris contraction and relaxation cycles, creating pressure differentials that drive fluid outflow continuously, preventing occlusion and maintaining reliable pressure reduction without requiring repeated surgeries.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The implant harnesses the body's own iris pump mechanism to drive fluid drainage. By attaching the pump to the iris tissue, the system uses the natural contraction and relaxation of the iris muscle during pupil response to light changes as the driving force for aqueous humor outflow, eliminating the need for external power sources or complex control systems.

Inventive Principle:
Principle #25Self-service

2Device complexity

If passive drainage system is used, then device complexity is reduced, but occlusion occurs and intraocular pressure does not decrease when pressure is similar on both sides

Engineering Contradiction:
Improvecomplexity of pump mechanismVSAvoideffectiveness of intraocular pressure reduction
Core Design Contradiction:
Device complexityVSReliability

Solution Approach 1:

The system introduces dynamic volume changes to the trabecular meshwork through iris-driven pumping action. The alternating compression and expansion of the meshwork creates continuous pressure differentials that drive fluid outflow, preventing the pressure equalization that causes occlusion in passive systems. This dynamic mechanism maintains reliable pressure reduction without requiring overly complex external control systems.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The pump operates through periodic iris contraction and relaxation cycles, creating intermittent but continuous pumping action. This periodic volume change in the trabecular meshwork ensures continuous fluid outflow by preventing pressure equalization, maintaining effective pressure reduction while keeping the mechanism relatively simple and biocompatible.

Inventive Principle:
Principle #19Periodic action

3Productivity

If channel opening surgery is performed, then drainage path is created, but clogging occurs over time requiring repeated operations

Engineering Contradiction:
Improvedrainage efficiencyVSAvoidduration of drainage channel patency
Core Design Contradiction:
ProductivityVSDuration of action of stationary object

Solution Approach 1:

The implant creates a dynamic drainage system where the trabecular meshwork is actively compressed and expanded by iris movements. This continuous mechanical action prevents fluid stasis and clogging in the drainage channels, maintaining open pathways for prolonged periods. The active pumping mechanism ensures continuous fluid flow without requiring repeated surgical interventions to clear blocked channels.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The pump mechanism provides continuous pumping action throughout the day as the iris naturally responds to light changes. This uninterrupted volume change in the trabecular meshwork maintains continuous fluid outflow and prevents channel occlusion, extending the duration of effective drainage without the need for repeated surgeries to restore patency.

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This active pumping mechanism effectively reduces intraocular pressure by enhancing fluid outflow through the trabecular meshwork, preventing vision loss and avoiding the limitations of passive systems, including occlusion and the need for repeated surgeries.

Implementation Method 1

the implant acts as an active pump by utilizing diameter change of pupil and iris caused by light variations

Methodology Applied
Scientific EffectIris pump mechanism: Mechanical Force

Implementation Method 2

diameter change of pupil and iris caused by light variations

Methodology Applied
Scientific EffectLight variation response: Light

Implementation Method 3

employing a flexible string to transmit tensile force and expand holes in the trabecular meshwork for unidirectional fluid flow

Methodology Applied
Scientific EffectTensile force transmission: Tension

Implementation Method 4

This active pumping mechanism effectively reduces intraocular pressure by enhancing fluid outflow through the trabecular meshwork

Methodology Applied
Scientific EffectPressure differential: Pressure Gradient

Data Source

PatentUS11116662B2Glaucoma pump implant working by means of iris movements to reduce intraocular pressure
Publication Date: 2021.09.14 CINAL ADNAN
  • US11116662B2 patent drawing
  • US11116662B2 patent drawing
  • US11116662B2 patent drawing

AI summary

The invention relates to glaucoma pump implant (100) developed for use in reducing intra ocular pressure of glaucoma patients. The invention particularly relates to a glaucoma pump implant (100) that allows the glaucoma pump implant (100) to act as an active pump by utilizing diameter changes of pupil (210) and iris (220) caused by light variations.