Noninvasive Glucose Analyzer via Dermal Layer Modulation
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Solution Overview
Problem
There is a need for a noninvasive method to determine glucose concentration in the human body effectively, as existing technologies are inadequate in this regard.
Innovation Solution
A noninvasive glucose concentration analyzer system that uses an applied force-optic analyzer to modulate skin tissue layers by applying physical forces, altering optical pathways and allowing for the noninvasive determination of glucose concentration through spectrometry, by selecting specific illumination and detection zones that target the dermal layer without penetrating the subcutaneous fat layer.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If optical pathways penetrate deeper into tissue to detect glucose, then detection capability is improved, but subcutaneous fat layer interference increases
Solution Approach 1:
The patent applies local quality by selecting specific detection zones within the dermal layer that have different optical properties. By choosing illumination and detection zones that target specific regions of the dermis while avoiding subcutaneous fat, the system achieves localized optimal detection conditions. This is accomplished through configuring multiple detectors at different radial distances to sample from specific tissue depths and locations.
Solution Approach 2:
The patent transitions from single-point detection to multi-dimensional spatial sampling by arranging detectors at various radial distances from the illumination zone. This creates a three-dimensional sampling pattern that enables selection of optical pathways based on depth and lateral position, allowing the system to probe specific tissue layers while avoiding interfering structures like subcutaneous fat.
2Measurement precision
If multiple illumination zone-to-detection zone distances are used, then sampling of common tissue layer is improved, but device complexity increases
Solution Approach 1:
The patent segments the detection function by dividing the tissue sampling task into multiple independent optical pathways, each with a specific illumination zone-to-detection zone distance. Each pathway samples a particular tissue depth or region, and the results are combined to achieve comprehensive and accurate tissue layer sampling. This segmentation allows the system to probe different depths without requiring a single complex adjustable mechanism.
Solution Approach 2:
The patent achieves multi-functionality by configuring a single analyzer device to perform multiple sampling functions simultaneously through its array of detectors at different radial distances. The same device can sample from various tissue depths and locations by selecting different detector elements, eliminating the need for multiple separate instruments or complex mechanical adjustment mechanisms.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enables accurate and noninvasive glucose monitoring by altering skin tissue properties with applied forces, enhancing the detection of glucose concentration through modified optical pathways, providing a reliable and minimally invasive method for glucose determination.
Implementation Method 1
modulate skin tissue layers by applying physical forces, altering optical pathways
Implementation Method 2
determination of glucose concentration through spectrometry
Data Source
AI summary
The invention comprises a method and apparatus for selecting optical pathways sampling a common tissue position, such as a lateral mean range in the dermis, of a person for analysis in a noninvasive analyte property determination system, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and selecting, using a metric, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.