Noninvasive Glucose Analyzer Using Optical Pathway Modulation
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Solution Overview
Problem
There is a need for a noninvasive method to determine glucose concentration in the human body effectively, as existing technologies face challenges in accurately measuring glucose levels without invasive procedures.
Innovation Solution
A noninvasive glucose concentration analyzer system that uses an applied force-optic analyzer to modulate skin tissue layers by applying physical forces, altering optical pathways and allowing photons to interact with the dermis without entering the subcutaneous fat layer, enabling noninvasive glucose concentration determination through spectrometric analysis.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If invasive procedures are used to measure glucose concentration, then measurement precision is improved, but ease of operation deteriorates
Solution Approach 1:
The patent replaces the mechanical/invasive sampling system (blood draws, needle insertions) with an optical field-based system. Light sources emit photons that penetrate tissue to detect glucose concentration noninvasively, substituting mechanical intrusion with optical interaction. This resolves the contradiction by eliminating the invasive aspect while maintaining measurement capability through spectroscopic analysis of tissue-optical path interactions.
Solution Approach 2:
The patent introduces optical pathways as an intermediary medium between the measurement system and the glucose molecules. Instead of direct contact with blood or tissue fluids, the system uses light transmission through tissue layers (epidermis, dermis, subcutaneous fat) as an intermediary to indirectly detect glucose concentration. This intermediary optical field enables noninvasive measurement while preserving measurement precision through spectral analysis.
2Measurement precision
If optical pathways penetrate deeper into tissue, then glucose detection capability is improved, but harmful factors increase due to subcutaneous fat layer interference
Solution Approach 1:
The patent applies local quality by targeting specific tissue regions with controlled optical penetration depth. The system focuses measurements on the dermis layer where glucose is present, using wavelength selection and path length control to ensure optical pathways remain within the dermis and do not extend into the subcutaneous fat layer. This localized approach maintains glucose detection capability while avoiding the harmful interference of fat layer absorption.
Solution Approach 2:
The patent utilizes parameter changes by varying optical wavelength and path length to control penetration depth. By selecting specific wavelength ranges and adjusting the illumination-detection geometry, the system modifies the optical pathways to achieve optimal penetration into the dermis without reaching the subcutaneous fat layer. This parameter control enables precise depth management to avoid fat layer interference while maintaining glucose detection sensitivity.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system effectively determines glucose concentration by modulating skin tissue layers, enhancing perfusion and altering scattering coefficients, allowing for accurate noninvasive glucose measurement using visible and near-infrared regions, thereby overcoming the limitations of invasive methods.
Implementation Method 1
modulate skin tissue layers by applying physical forces, altering optical pathways
Implementation Method 2
allowing photons to interact with the dermis without entering the subcutaneous fat layer
Implementation Method 3
enabling noninvasive glucose concentration determination through spectrometric analysis
Data Source
AI summary
The invention comprises a method and apparatus for selecting optical pathways sampling a common tissue layer, such as the dermis, of a person for analysis in a noninvasive analyte property determination systemy, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and selecting, using a metric, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.