Noninvasive Glucose Analyzer Skin Modulation
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Solution Overview
Problem
There is a need for a noninvasive method to determine glucose concentration in the human body effectively, as existing technologies face challenges in accurately measuring glucose levels without invasive procedures.
Innovation Solution
A noninvasive glucose concentration analyzer system that uses an applied force-optic analyzer to modulate skin tissue layers, employing a force system to apply physical distortions and a spectrometer to collect spectra, allowing for noninvasive determination of glucose concentration by analyzing changes in optical pathways through the skin's dermal layers.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If invasive procedures are used to measure glucose concentration, then measurement precision is improved, but ease of operation deteriorates
Solution Approach 1:
The patent replaces the mechanical/invasive sampling system with an optical detection system. Instead of using needles or other invasive mechanical means to obtain blood samples, the invention uses light sources and detectors to noninvasively measure glucose concentration through optical absorption and scattering properties of tissue, thereby eliminating the harmful effects of invasive procedures while maintaining measurement capability
Solution Approach 2:
The patent introduces optical radiation (light) as an intermediary medium to transmit information about glucose concentration from the body tissue to the detector. The light acts as a mediator that interacts with the tissue and carries information about glucose levels without requiring direct contact or invasion, enabling noninvasive measurement while preserving measurement precision
2Loss of information
If optical pathways penetrate deeper into tissue, then more glucose information is obtained, but subcutaneous fat layer interference increases
Solution Approach 1:
The patent applies local quality by selecting specific wavelength ranges that have different penetration depths and interaction characteristics with various tissue components. By using multiple wavelength ranges (including visible and near-infrared regions), the system can target specific tissue layers and optimize the detection of glucose information while minimizing interference from subcutaneous fat, as different wavelengths interact differently with various tissue types
Solution Approach 2:
The patent employs dynamic modulation of skin tissue layers through applied force to temporarily alter tissue structure and enhance perfusion. This dynamic adjustment allows the optical pathways to access deeper tissue regions containing glucose information while the modulation creates temporary windows that reduce scattering and interference from intermediate layers like subcutaneous fat, enabling selective access to desired tissue depths
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system enables accurate and noninvasive measurement of glucose levels by modulating skin tissue layers to enhance perfusion and alter optical paths, allowing for precise detection of glucose concentration without penetrating the subcutaneous fat layer, thereby overcoming the limitations of invasive methods.
Implementation Method 1
employing a force system to apply physical distortions
Implementation Method 2
a spectrometer to collect spectra, allowing for noninvasive determination of glucose concentration by analyzing changes in optical pathways
Data Source
AI summary
The invention comprises a method and apparatus for sampling optical pathways having a common tissue depth, such as a maximum mean depth of penetration in the dermis, with a common detector of a person for analysis in a noninvasive analyte property determination system, comprising the steps of: probing skin with a range of illumination zone-to-detection zone distances with at least two wavelength ranges, which optionally overlap, and detecting, using a common detector, illumination zone-to-detection zone distances having mean optical pathways probing the common tissue layer, such as without the mean optical pathways entering the subcutaneous fat layer of the person. Optionally, the skin tissue layers are modulated and/or treated via tissue displacement before and/or during data collection.