Reaction Site Temperature Estimation in Blood Glucose Devices

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Solution Overview

Problem

Blood glucose monitors integrated into portable electronic devices face challenges in accurately estimating the temperature at the reaction site due to internal heat generation from components like power supplies and microcontrollers, which can fluctuate based on device usage, leading to inaccurate glucose measurements.

Innovation Solution

A dynamic thermal model is employed to estimate the reaction site temperature by determining the activation initiation time, duration, and thermal magnitude of heat generating components, calculating a total temperature elevation, and subtracting this from the internal temperature reading to provide an accurate estimation of the reaction site temperature.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If an internal temperature sensor is used to measure the temperature at the reaction site, then the temperature can be monitored, but the measurement becomes inaccurate due to internal heat generation from electronic components

Engineering Contradiction:
Improvetemperature measurement accuracyVSAvoidinternal heat generation
Core Design Contradiction:
Measurement precisionVSObject-generated harmful factors

Solution Approach 1:

The patent introduces a thermal model as an intermediary between the internal temperature sensor and the reaction site temperature estimation. The thermal model accounts for heat transfer paths and thermal resistance between electronic components and the reaction site, allowing accurate temperature estimation without direct thermal contact that would cause heating.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces direct thermal measurement (mechanical/physical contact) with a computational approach using a thermal model. Instead of relying on physical proximity that causes heat transfer, the system uses mathematical modeling based on measured temperatures and known thermal characteristics to estimate the reaction site temperature.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Adaptability or versatility

If the blood glucose monitor is integrated into a portable electronic device, then device functionality is enhanced, but temperature measurement accuracy deteriorates due to fluctuating internal temperatures

Engineering Contradiction:
Improvedevice integrationVSAvoidreaction site temperature estimation
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The patent implements a dynamic thermal model that continuously adapts to changing operating conditions. The model is updated based on real-time temperature measurements from internal sensors and adjusts its parameters to reflect current device usage patterns, allowing accurate temperature estimation despite fluctuating internal temperatures from various electronic components.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system uses feedback from internal temperature sensors to continuously refine the thermal model's estimation of reaction site temperature. The measured temperatures from various points in the device are fed back into the thermal model, which adjusts its calculations to account for current heat generation patterns, ensuring accurate temperature compensation throughout device operation.

Inventive Principle:
Principle #23Feedback

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for accurate estimation of the reaction site temperature, preventing unwarranted lockout conditions and ensuring reliable blood glucose measurements by accounting for device usage and internal heat variations.

Implementation Method 1

a temperature measuring element operable to measure an internal temperature of the blood glucose measuring device

Methodology Applied
Scientific EffectTemperature sensing: Thermistor

Implementation Method 2

many portable devices generate significant internal heat resulting from active and passive components within the device, such as power supplies, resistors, integrated circuits, microcontrollers

Methodology Applied
Scientific EffectJoule heating: Joule Heating

Data Source

PatentUS8140294B2Temperature estimations in a blood glucose measuring device
Publication Date: 2012.03.20 ROCHE DIABETES CARE INC
  • US8140294B2 patent drawing
  • US8140294B2 patent drawing
  • US8140294B2 patent drawing

AI summary

Methods of estimating the temperature of a reaction site on a measurement strip in a blood glucose measuring devices are provided. In one embodiment, a method includes determining an activation initiation time, an activation duration time, a thermal magnitude and a temperature elevation for heat generating components within a device. The temperature elevation for each of the heat generating components is determined at least in part by an impulse response matrix [Xi], the activation initiation time, the activation duration time and the thermal magnitude for each of the heat generating components. The method further includes determining a total temperature elevation of the glucose measuring device by summing the temperature elevation of each of the heat generating components, reading a temperature value provided by the temperature measuring element, and determining a reaction site temperature estimation by subtracting the total temperature elevation from the temperature value provided by the temperature measuring element.