Artificial Pancreas Event Detection from Blood Glucose Difference Rates

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Solution Overview

Problem

Current artificial pancreas systems require manual input of meal and exercise information for closed-loop control, limiting them to semi-closed-loop operation.

Innovation Solution

An automatic detection method based on the change rate of the difference between actual blood glucose values, combined with other judgment results, to determine meal or exercise events and adjust infusion strategies accordingly.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Extent of automation

If manual input of meal and exercise information is required, then the artificial pancreas can adjust infusion strategy, but the system cannot achieve closed-loop control and requires user intervention

Engineering Contradiction:
Improveautomatic meal and exercise detectionVSAvoiddetection and judgment mechanism
Core Design Contradiction:
Extent of automationVSDevice complexity

Solution Approach 1:

The system automatically detects meal and exercise events by monitoring blood glucose changes without requiring user input. The detection module continuously monitors glucose levels, and the judgment module automatically identifies events based on predefined criteria, enabling the artificial pancreas to self-adjust infusion strategies without user intervention.

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system uses feedback from continuous blood glucose monitoring to trigger automatic detection of meal and exercise events. When blood glucose changes exceed threshold values, the judgment module identifies the event type and adjusts infusion parameters accordingly, creating a closed-loop control system that responds automatically to physiological changes.

Inventive Principle:
Principle #23Feedback

2Measurement precision

If continuous blood glucose monitoring is performed, then real-time data is available, but the detection device must be attached to skin and sensor inserted into interstitial fluid

Engineering Contradiction:
Improvecontinuous blood glucose detectionVSAvoiddevice attachment and sensor insertion
Core Design Contradiction:
Measurement precisionVSEase of operation

Solution Approach 1:

The system uses interstitial fluid as an intermediary medium to indirectly measure blood glucose levels. The sensor detects glucose concentration in the interstitial fluid, which correlates with blood glucose levels, providing continuous monitoring without requiring direct blood sampling or complex skin attachment procedures.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Extent of automation

If automatic event detection is implemented, then closed-loop control is achieved, but the system may misidentify events without additional judgment criteria

Engineering Contradiction:
Improveautomatic event detectionVSAvoidevent type identification accuracy
Core Design Contradiction:
Extent of automationVSReliability

Solution Approach 1:

The judgment module applies different detection criteria and threshold values for different event types (meal events vs. exercise events). By analyzing the specific characteristics and patterns of blood glucose changes associated with each event type, the system accurately distinguishes between them and avoids misidentification, ensuring reliable automatic detection.

Inventive Principle:
Principle #3Local quality

Data Source

PatentEP4675641A1Automatic monitoring method based on rate of change of difference between actual blood glucose values, and closed-loop artificial pancreas
Publication Date: 2026.01.07 MEDTRUM TECH
  • EP4675641A1 patent drawingFigure 1
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  • EP4675641A1 patent drawingFigure 3

AI summary

The invention discloses an automatic detection method based on the change rate of the difference between the actual blood glucose values, including: obtaining an actual blood glucose value of the user at the current time; obtaining a historical actual blood glucose value of the user at the previous time, and calculate a difference between the actual blood glucose values at the current time and at the previous time; calculating a change rate of the difference between the actual blood glucose values at the current time; and comparing the change rate of the difference between the actual blood glucose values at the current time with a preset threshold, and determining an event type according to the comparing result. According to the determined event type, the artificial pancreas can automatically adjust the corresponding infusion strategy to achieve closed-loop control of the artificial pancreas.