Glucose-Insulin Prediction via Segmented Probabilistic Frameworks

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Solution Overview

Problem

Current predictive data analysis technologies face challenges in accurately detecting glucose surge excursions and efficiently generating glucose-insulin predictions in the glucose-insulin endocrine metabolic regulatory system, particularly in terms of computational efficiency and reliability.

Innovation Solution

The implementation of probabilistic frameworks for detecting glucose surge excursions using statistical properties and machine learning models, such as steady-state glucose-insulin prediction models, along with parameter optimization techniques to refine model parameters and improve prediction accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If complex machine learning models are used to detect glucose surge excursions and generate predictions, then prediction accuracy is improved, but computational efficiency deteriorates

Engineering Contradiction:
Improveprediction accuracyVSAvoidcomputational efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent segments the prediction process into multiple components: excursion detection module, steady-state prediction module, and parameter optimization module. This segmentation allows each component to handle specific tasks efficiently, improving overall computational efficiency while maintaining accuracy through specialized processing at each stage.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs parameter optimization techniques that dynamically adjust model parameters based on input data characteristics. By changing parameters adaptively, the system achieves high prediction accuracy without requiring consistently complex computational models, thus improving computational efficiency.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If probabilistic frameworks and statistical properties are used for detecting glucose surge excursions, then detection reliability is improved, but device complexity increases

Engineering Contradiction:
Improvedetection reliabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent introduces probabilistic frameworks as intermediary layers between raw CGM data and prediction outputs. These frameworks act as mediators that process data through statistical properties to generate reliable detections, managing complexity through structured intermediate representations rather than direct complex processing.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system incorporates feedback mechanisms where prediction results and detection reliability metrics are used to optimize future detections. This feedback loop improves reliability over time while managing complexity through iterative refinement rather than requiring overly complex initial designs.

Inventive Principle:
Principle #23Feedback

3Reliability

If steady-state glucose-insulin prediction models are used, then physiological insight is improved, but model complexity increases

Engineering Contradiction:
Improvephysiological insightVSAvoidmodel complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts and focuses on steady-state conditions from the broader glucose-insulin dynamics. By isolating and analyzing only the steady-state portions of the data, the model achieves deep physiological insight without needing to process the entire complex temporal dynamics, thus reducing overall model complexity.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The system applies partial analysis by focusing computational resources specifically on steady-state intervals rather than continuously processing all data. This partial action approach provides sufficient physiological insight for clinical decision-making without requiring full comprehensive modeling of all physiological states.

Inventive Principle:
Principle #16Partial or excessive action

Data Source

PatentUS12186109B2Predictive monitoring of the glucose-insulin endocrine metabolic regulatory system
Publication Date: 2025.01.07 UNITEDHEALTH GROUP INC
  • US12186109B2 patent drawing
  • US12186109B2 patent drawing
  • US12186109B2 patent drawing

AI summary

There is a need for more effective and efficient predictive data analysis, such as more effective and efficient data analysis solutions for performing predictive monitoring of the glucose-insulin endocrine metabolic regulatory system. Certain embodiments utilize systems, methods, and computer program products that perform predictive data analysis by utilizing at least one of glucose surge excursion detections, steady-state glucose-insulin machine learning models, and parameter space refinement machine learning models.