Blood Glucose Meter Reagent Scattering Detection

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Solution Overview

Problem

Conventional biosensor technologies fail to detect defective analytical devices due to reagent scattering on hematocrit electrodes, which prevents accurate hematocrit and glucose level measurements.

Innovation Solution

A method and apparatus that apply a detection signal to test electrode pairs to measure electrical responses, determining the presence or absence of reagent scattering by comparing the responses with known values, allowing for the identification of defective devices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a separated element is located between hematocrit electrodes and glucose electrodes to prevent interference, then measurement reliability is improved, but device complexity increases due to additional structural components

Engineering Contradiction:
Improvemeasurement reliabilityVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts the detection function for reagent scattering from the main measurement process. By applying a detection signal specifically to the hematocrit electrodes before the reagent is applied, the system can detect scattered reagent separately from the actual hematocrit and glucose measurements, thus maintaining measurement reliability without requiring complex physical barriers

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent performs a preliminary detection of reagent scattering on the hematocrit electrodes before the reagent interferes with the actual measurements. This preliminary action allows the system to identify defective analytical devices early, preventing erroneous measurements while avoiding the need for complex structural separations

Inventive Principle:
Principle #10Preliminary action

2Device complexity

If reagent scattering on hematocrit electrodes is not detected, then device complexity remains low, but measurement precision deteriorates due to interference with hematocrit and glucose level measurements

Engineering Contradiction:
Improvedevice complexityVSAvoidmeasurement precision
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent implements a feedback mechanism where the detection signal applied to the hematocrit electrodes provides information about reagent scattering. This feedback allows the control unit to identify when scattered reagent is present and prevent erroneous measurements, thereby maintaining measurement precision without adding complex physical structures

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The patent replaces potential mechanical separation structures with an electrical detection system. Instead of using physical barriers or complex structural arrangements to prevent reagent interference, the system uses electrical signals to detect scattered reagent on the hematocrit electrodes, achieving measurement precision through electrical means rather than mechanical design

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

3Reliability

If detection signal is applied to test electrode pairs to identify reagent scattering, then measurement reliability is improved, but loss of time occurs due to additional detection steps

Engineering Contradiction:
Improvemeasurement reliabilityVSAvoidloss of time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The detection of reagent scattering is performed as a preliminary step before the actual hematocrit and glucose measurements. By detecting scattered reagent first, the system can quickly identify defective analytical devices and avoid time-consuming erroneous measurements, thus the time loss is minimal and only occurs when necessary

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent allows the system to skip the actual measurement process when reagent scattering is detected. Instead of proceeding with time-consuming hematocrit and glucose measurements that would be erroneous, the system rapidly identifies the defect and terminates the measurement sequence, reducing overall time loss by avoiding futile measurements

Inventive Principle:
Principle #21Skipping (Rushing through)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables the detection of reagent scattering on hematocrit electrodes, ensuring accurate measurement of biological values and correcting glucose levels in biosensor systems.

Implementation Method 1

measuring an electrical response to a detection signal applied to at least one test electrode pair

Methodology Applied
Scientific EffectElectrical response measurement: Conduction (electrical)

Data Source

PatentEP2871471B1Measuring apparatus and measuring method
Publication Date: 2019.02.27 ARKRAY INC
  • EP2871471B1 patent drawingFigure 1
  • EP2871471B1 patent drawingFigure 2
  • EP2871471B1 patent drawingFigure 3~4

AI summary

An apparatus and a method that can detect a defective analytical device due to the scattering of a reagent are provided. In particular, a blood glucose level meter (measuring apparatus) 1 is configured to measure a target component of a biological sample using a reagent. The apparatus includes a second measuring unit (measuring unit) 31b configured to measure an electrical response to a detection signal applied to a pair of hematocrit electrodes (test electrode pair), and a control unit 33 configured to determine the presence or absence of the reagent on the pair of hematocrit electrodes based on the measured electrical response.