Subcutaneous Glucose Sensor Pre-Grace Period Stabilization
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
Current subcutaneous glucose monitoring systems face inaccuracies during the initial warm-up and stabilization periods, leading to reduced service life due to sensor reactions with the body, resulting in unstable signal measurements and shorter effective usage time compared to the announced service life.
Innovation Solution
A subcutaneous glucose monitoring system with a pre-grace period that allows for adaptation to individual implant reactions, where data is not displayed during this period, and the system automatically adjusts the display period to ensure accurate measurements throughout the predetermined usage time, eliminating the need for calibration of the second sensor upon replacement.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If the sensor is implanted subcutaneously to measure glucose concentration, then continuous monitoring capability is achieved, but the sensor requires a warm-up period of 30-120 minutes before accurate measurement, during which time the measured data is unstable and inaccurate
Solution Approach 1:
The system performs preliminary actions by implementing a pre-grace period before the official measurement period begins. During this pre-grace period, the sensor is allowed to stabilize and adapt to the implantation site, performing necessary calibration and equilibration activities. This preliminary action ensures that when the measurement period starts, the sensor is already in an optimal state for accurate glucose measurement, thereby reducing the effective warm-up time within the billed service period.
2Duration of action of stationary object
If the sensor service life is extended to 15 days as announced by makers, then the usage duration is improved, but the effective measurement time is reduced to only 9.72-13.72 days due to warm-up period and unstable measurement period of 1-5 days
Solution Approach 1:
The system implements a pre-grace period at the beginning of the sensor service life where stabilization activities occur before the official measurement period. This preliminary action separates the warm-up and stabilization time from the billed service period, allowing the full 15-day service life to deliver accurate measurements. The pre-grace period handles the unstable initial phase, ensuring that the entire service period provides reliable data.
Solution Approach 2:
The sensor service life is segmented into distinct periods: a pre-grace period for stabilization, and a subsequent measurement period for accurate monitoring. This segmentation allows the system to account for the unstable initial phase separately from the reliable measurement phase, ensuring that the billed service life reflects only the period when accurate measurements are provided.
3Reliability
If the sensor is implanted to provide continuous glucose monitoring, then real-time data is obtained, but inflammatory responses and wound reactions occur causing signal instability and reduced measurement reliability
Solution Approach 1:
The system implements a pre-grace period that allows the sensor to adapt to the implantation site and for the body to respond to the foreign object before official measurements begin. This preliminary period accommodates the inflammatory response and wound healing process, allowing signals to stabilize before the measurement period starts. By delaying the start of the measurement period until after this adaptation phase, the system ensures more reliable and stable glucose readings throughout the service life.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach extends the effective measurement period, ensuring accurate data display for the announced service life, maintains continuous monitoring, and simplifies sensor transitions, reducing the risk of interrupted glucose level monitoring and improving user experience.
Implementation Method 1
a sensor having a predetermined usage time length, wherein at least a part of the sensor is configured to be implanted subcutaneously in a living body in contact with a biological fluid to output a measured signal or a data indicating a glucose level in the biological fluid
Data Source
AI summary
A subcutaneous glucose monitoring system is disclosed. The subcutaneous glucose monitoring system includes a glucose measurement device that includes a sensor having a predetermined usage time length, and a reader comprising a processor, a wireless communication module, a memory, and a user interface configured to couple with the one or more processors and be operated by the user to set the pre-grace period and display the data. The processor is configured to execute the following steps according to the instruction: providing the pre-grace period for the user to be set on the user interface, wherein the pre-grace period is configured to be adjusted to a specific time length in response to a specific implant reaction; displaying none of the data on the user interface during the pre-grace period; enabling the user interface to display the data during a data display period in the predetermined usage time length after the pre-grace period expires; and when the data display period expires, causing the user interface to stop displaying the data.