Subcutaneous Glucose Sensor Temperature Control
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Solution Overview
Problem
Conventional electrochemical sensors for measuring glucose concentration in body fluids face challenges in maintaining measurement reliability and reproducibility due to fluctuations in ambient temperature, leading to complex temperature correction algorithms that often fail to accurately cancel out temperature-related influences.
Innovation Solution
A monitoring device with an electrochemical sensor and a temperature control unit that adjusts the ambient temperature to a target setting temperature, using a Peltier device to maintain the temperature within a specified range, thereby eliminating the need for temperature correction and enhancing measurement reliability and reproducibility.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If temperature correction algorithms are used to compensate for ambient temperature fluctuations, then measurement reliability can be improved, but the device complexity and algorithm sophistication become excessively high
Solution Approach 1:
The patent extracts the temperature control function from the measurement system and implements it as a separate temperature control unit with heating and cooling elements. This physical separation allows the measurement electrode to operate in a thermally controlled environment without requiring complex temperature correction algorithms, thus improving reliability while reducing computational complexity.
Solution Approach 2:
The temperature control unit performs preliminary temperature stabilization before measurements are taken. By maintaining the ambient temperature within a predetermined range in advance, the system prevents temperature-related measurement errors rather than correcting them afterward, eliminating the need for complex post-measurement correction algorithms.
2Measurement precision
If complex temperature correction algorithms are implemented, then temperature-related errors can be reduced, but the difficulty of detecting and measuring accurate glucose concentration increases
Solution Approach 1:
The patent introduces a temperature control unit as an intermediary between the measurement electrode and the external environment. This intermediary actively maintains a stable thermal environment around the electrode, preventing temperature fluctuations from affecting measurements. This physical mediation simplifies the measurement process by eliminating the need for complex temperature compensation calculations.
3Device complexity
If the ambient temperature is allowed to fluctuate freely, then the device structure remains simple, but the measurement reliability and reproducibility deteriorate due to temperature effects on enzyme activity
Solution Approach 1:
The temperature control unit operates autonomously to maintain the ambient temperature within the predetermined range. It continuously monitors temperature conditions and automatically activates heating or cooling elements as needed, serving itself to maintain optimal measurement conditions without requiring complex external control systems or algorithms.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The solution effectively maintains the ambient temperature at a stable level, reducing the impact of temperature fluctuations on measurement results and improving the reliability and reproducibility of glucose concentration measurements in body fluids.
Implementation Method 1
A monitoring device with an electrochemical sensor and a temperature control unit that adjusts the ambient temperature to a target setting temperature, using a Peltier device to maintain the temperature within a specified range
Implementation Method 2
The electrochemical sensor is a sensor capable of detecting a minute amount of electric current by making use of electrochemical reaction
Implementation Method 3
The glucose oxidase produces gluconic acid by selectively reacting on the glucose under an existence of oxygen. On this occasion, the oxygen is reduced, while hydrogen peroxide proportional to a quantity of the glucose is generated
Implementation Method 4
The electrochemical sensor is a sensor capable of detecting a minute amount of electric current by making use of electrochemical reaction, and is suited to detecting a minute amount of chemical substance in which oxidation-reduction reaction occurs
Data Source
AI summary
A monitoring device which measures numerical value information on a subject substance in a body fluid has an electrochemical sensor including a sensor unit for detecting the subject substance which is used in the way of being embedded subcutaneously and generating an electric signal correlating to the numerical value information on the subject substance, and a temperature control unit which adjusts the detected ambient temperature as a temperature ambient to a sensor unit when detecting the subject substance so as to reach a target setting temperature when measuring the subject substance.