Glucose Smoothing Algorithm for Consistency Checks
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Solution Overview
Problem
Current blood glucose monitoring systems, particularly for diabetes management, face challenges with frequent finger-stick tests being burdensome and providing only point-in-time data, lacking information on intraday fluctuations, which can impact glycemic control and patient adherence.
Innovation Solution
A system comprising a display device with a transceiver interface, user interface, and computer that calculates smoothed glucose values using different polynomial smoothing algorithms to recalculate values based on threshold alarms, ensuring consistency and displaying these smoothed values without the raw data points, enhancing user interaction and glycemic control.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If finger-stick blood glucose tests are performed frequently to achieve tight glycemic control, then measurement precision is improved, but patient adherence deteriorates due to burden
Solution Approach 1:
The patent replaces the mechanical finger-stick testing system with a continuous glucose monitoring system that uses an implantable sensor and wireless transmitter to automatically measure and transmit glucose levels, eliminating the need for repeated manual punctures and improving patient adherence while maintaining measurement precision
Solution Approach 2:
The continuous glucose monitoring system enables self-service by automatically and continuously measuring glucose levels without requiring patient intervention for each measurement, with the sensor autonomously providing data that is wirelessly transmitted to a receiver for display and analysis
2Device complexity
If finger-stick measurements are used to monitor blood glucose, then device complexity is reduced, but information completeness deteriorates as only point-in-time data is provided
Solution Approach 1:
The patent implements continuous glucose monitoring by having the implantable sensor continuously measure glucose levels in interstitial fluid and automatically transmit data at frequent intervals (e.g., every 5 minutes), providing complete intraday fluctuation information rather than isolated point-in-time measurements
Solution Approach 2:
The system transitions from one-dimensional point-in-time measurements to multi-dimensional continuous data collection by measuring glucose levels across multiple time points throughout the day, enabling comprehensive analysis of glucose patterns, trends, and fluctuations
3Measurement precision
If raw glucose values are displayed directly to users, then data accuracy is improved, but user interface complexity increases making it less user-friendly
Solution Approach 1:
The patent introduces smoothed glucose values as an intermediary representation that mediates between raw sensor data and user interpretation, applying algorithms to filter noise and highlight meaningful trends while preserving accurate glucose information in a more user-friendly format
Solution Approach 2:
The system transforms raw glucose data by applying smoothing algorithms that modify the parameter representation from individual noisy measurements to averaged trend values, maintaining data accuracy while improving interpretability for users
Data Source
AI summary
A display device configured to receive raw values, calculate smoothed values, and display the smoothed values only if the smoothed values satisfy a consistency check. In some embodiments, the consistency check may be satisfied if none of the smoothed values (i) corresponds to a raw value that triggered a first or second alarm and (ii) would not also trigger the first or second alarm. In some embodiments, if the smoothed values do not satisfy the consistency check, the display device may re-calculate the smoothed values such that the consistency check is satisfied. The display device may display the smoothed values in place of corresponding raw values in a historical trend graph.