Glue Concentration Analysis in Electrolyte via HPLC
Find Innovative SolutionsGenerate Solutions
Solution Overview
Problem
The challenge lies in accurately analyzing the low concentration of glue in electrolyte solutions, particularly in copper electrolysis, where existing methods are complex and prone to glue degradation due to high sulfuric acid content, making it difficult to obtain reliable results.
Innovation Solution
A high-performance liquid chromatography method using a pH-adjusted aqueous phosphate solution as the mobile phase and a separation column with an exclusion limit molecular weight of 4000-6000, along with a hydrophilic vinyl polymer filler, simplifies the analysis and reduces glue degradation by using only one separation column and avoiding organic solvents like acetonitrile.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If high performance liquid chromatography with two separation columns is used to analyze glue concentration, then the analysis can separate glue from electrolyte components, but the system becomes complex and glue degradation may occur during passing through multiple columns
Solution Approach 1:
The patent combines the separation and detection functions into a single integrated column system. The single column is designed with specific pore size and stationary phase that can simultaneously separate glue from electrolyte components and detect the glue concentration, eliminating the need for two separate columns and reducing system complexity while maintaining analysis accuracy.
Solution Approach 2:
The patent extracts and eliminates the intermediate transfer step between two columns by using a single column design. This removes the potential degradation risk during transfer and simplifies the overall system architecture while preserving the separation and detection capabilities.
2Measurement precision
If acetonitrile is used as mobile phase to separate glue and electrolyte components, then separation efficiency is improved, but waste organic solution treatment becomes troublesome
Solution Approach 1:
The patent changes the mobile phase from organic solvent (acetonitrile) to aqueous buffer solution. By adjusting pH and ionic strength parameters of the aqueous buffer, the method achieves effective separation of glue from electrolyte components without requiring organic solvents, thereby eliminating waste treatment issues while maintaining separation efficiency.
3Measurement precision
If analysis time is extended to accurately measure low concentration glue, then measurement precision improves, but glue degradation by sulfuric acid increases
Solution Approach 1:
The patent applies preliminary protective action by adding antioxidants or adjusting buffer conditions before the analysis begins. This prevents glue degradation during the analysis process, allowing sufficient time for accurate detection of low concentration glue without compromising the integrity of the analyte.
Solution Approach 2:
The patent optimizes analysis parameters such as flow rate, temperature, and buffer composition to achieve fast separation. By reducing the overall analysis time through parameter optimization, the method maintains measurement precision for low concentration glue while minimizing degradation exposure time.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This method allows for easier and more accurate analysis of glue concentration, reducing the complexity of the system and minimizing glue degradation, while also simplifying waste treatment and analysis efficiency.
Implementation Method 1
passing the electrolyte solution-injected eluent through a separation column having an exclusion limit molecular weight of 4000-6000 to separate the glue and the electrolyte component
Implementation Method 2
detecting the separated glue by a detector
Data Source
AI summary
The purpose of the present invention is to provide a method to more easily analyze the concentration of glue in an electrolyte solution, while suppressing the degradation of glue during the analysis. There is provided a method for analyzing the concentration of glue contained in an electrolyte solution containing the electrolyte components by using high performance liquid chromatography, where said method comprises a step wherein an electrolyte solution is added into the eluent pH of which has been adjusted equal to or less than 5 by adding acid to an aqueous solution of phosphate of alkaline metal or alkaline earth metal, a step wherein the eluent into which the electrolyte solution has been added is passed through a separation column the exclusion limit molecular weight of which is 4000-6000 for separating the glue and electrolyte components, and a step wherein the separated glue is detected by a detector.