L-glufosinate and 2,4-D Choline Salt Synergy

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Solution Overview

Problem

Current herbicides, such as glufosinate and 2,4-D, have limitations in activity and target specificity, requiring improved combinations for effective broadleaf and grassy weed control without harming desirable plants, especially in pre- and post-emergence crops, and facing challenges with resistant weed varieties.

Innovation Solution

A synergistic combination of L-glufosinate or its salt and a choline salt of 2,4-D is developed, which can be applied pre- or post-emergence, providing efficient weed control by combining L-glufosinate's inhibition of glutamine synthetase with 2,4-D's systemic action, offering enhanced efficacy against a wide spectrum of weeds, including resistant varieties.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If glufosinate is used as a non-selective herbicide, then broad spectrum weed control is achieved, but crop damage occurs and selective control is lost

Engineering Contradiction:
Improvebroad spectrum weed controlVSAvoidcrop damage
Core Design Contradiction:
Adaptability or versatilityVSObject-affected harmful factors

Solution Approach 1:

The patent segments the herbicide spectrum into selective and non-selective components by combining glufosinate (non-selective) with 2,4-D (selective), allowing targeted control of specific weed types while preserving crop safety

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent merges glufosinate and 2,4-D into a combination product that integrates the broad-spectrum capability of glufosinate with the selective control of 2,4-D, achieving both versatility and crop safety simultaneously

Inventive Principle:
Principle #5Merging (Combining)

2Object-affected harmful factors

If 2,4-D is used for selective broadleaf weed control, then crop safety is maintained, but grassy weed control is insufficient

Engineering Contradiction:
Improvecrop safetyVSAvoidgrassy weed control
Core Design Contradiction:
Object-affected harmful factorsVSAdaptability or versatility

Solution Approach 1:

The patent combines 2,4-D's selective broadleaf control with glufosinate's grassy weed efficacy, creating a dual-mode herbicide system that maintains crop safety while expanding control capability to include grassy weeds

Inventive Principle:
Principle #5Merging (Combining)

3Productivity

If herbicide combinations are used to enhance activity, then weed control efficacy is improved, but formulation selection complexity increases

Engineering Contradiction:
Improveweed control efficacyVSAvoidformulation selection complexity
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The patent creates a universal formulation that can be applied across multiple crop types and weed scenarios, eliminating the need for separate formulations for different applications and simplifying selection while maintaining high efficacy

Inventive Principle:
Principle #6Universality (Multi-functionality)

4Reliability

If glufosinate is applied at high rates to control resistant weeds, then resistant variety control is improved, but chemical usage and cost increase

Engineering Contradiction:
Improveresistant variety controlVSAvoidchemical usage
Core Design Contradiction:
ReliabilityVSQuantity of substance

Solution Approach 1:

The patent merges glufosinate with 2,4-D in a synergistic combination that enhances the effectiveness of each component, allowing reduced chemical usage while maintaining control efficacy over resistant weeds through enhanced biological activity rather than increased dosage

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The combination demonstrates synergistic effects, providing effective control of both monocotyledonous and dicotyledonous weeds with reduced chemical usage, effective against resistant varieties, and showing improved weed control compared to individual herbicides, as evidenced by greenhouse trials using Colby's equation.

Implementation Method 1

The herbicidally active L-isomer of glufosinate is a structural analogue of glutamate and, therefore, is a competitive inhibitor of the enzyme glutamine synthetase (GS) of bacteria and plants

Methodology Applied
Scientific EffectEnzyme inhibition: Enzyme

Implementation Method 2

The herbicide kills weeds by disrupting plant hormone responses. It is a systemic herbicide which selectively kills most broadleaf weeds by causing uncontrolled growth in them

Methodology Applied
Scientific EffectHormone disruption:

Data Source

PatentUS20240108011A1Herbicidal combinations and compositions and methods for treating weeds using the same
Publication Date: 2024.04.04 UPL CORPORATION LTD(MU)

AI summary

Herbicidal combinations and compositions generally include L-glufosinate or a salt thereof, and a choline salt of 2,4-D. Also disclosed are methods of controlling weeds using the same.