Glufosinate and PPO Inhibitor Herbicide Combinations

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Solution Overview

Problem

Current herbicide combinations for controlling harmful plants or unwanted vegetation often lack sufficient herbicidal activity, have limited broad-spectrum effectiveness, and can cause damage to young plantation crops, leading to reduced harvest yields and inadequate long-lasting herbicidal action.

Innovation Solution

A specific combination of glufosinate, particularly its L-isomer, with protoporphyrinogen-IX oxidase inhibitors like Acifluorfen, Fomesafen, or Lactofen, in specific weight ratios, where the glufosinate component is present in higher amounts compared to the PPO-inhibitor, enhancing herbicidal activity and reducing the required application rates of the PPO-inhibitor.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current herbicide combinations are used, then herbicidal activity is provided, but the herbicidal activity is insufficient and spectrum effectiveness is limited

Engineering Contradiction:
Improveherbicidal activityVSAvoidspectrum effectiveness
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines glufosinate (a glutamine synthetase inhibitor) with PPO inhibitors (acifluorfen, fomesafen, or lactofen) to create a synergistic herbicide mixture. This merging of two different herbicide modes of action broadens the spectrum of weed control while maintaining high herbicidal activity, resolving the contradiction between sufficient herbicidal activity and spectrum effectiveness.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The invention creates a composite herbicide formulation with specific weight ratios (glufosinate at 50-95% and PPO inhibitor at 5-50%) that leverages the complementary properties of each component. The composite formulation achieves both high reliability in herbicidal activity and broad adaptability across different weed species.

Inventive Principle:
Principle #40Composite materials

2Reliability

If higher application rates are used to improve herbicidal activity, then initial activity increases, but damage to young plantation crops increases and harvest yields reduce

Engineering Contradiction:
Improveherbicidal activityVSAvoiddamage to young plantation crops
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the concentration parameters by using specific weight ratios of glufosinate to PPO inhibitor (50:50 to 95:5), allowing effective herbicidal activity at lower total application rates. This parameter optimization reduces the harmful effects on young plantation crops while maintaining high herbicidal reliability.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The PPO inhibitor acts as an intermediary that enhances the overall herbicidal effect of the combination, allowing lower doses of each individual herbicide to achieve the desired effect. This intermediary role of the PPO inhibitor with glufosinate reduces crop damage while maintaining high herbicidal activity.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If standard herbicide combinations are used, then broad-spectrum control is attempted, but long-lasting herbicidal action is inadequate

Engineering Contradiction:
Improvebroad-spectrum controlVSAvoidlong-lasting herbicidal action
Core Design Contradiction:
Adaptability or versatilityVSDuration of action of stationary object

Solution Approach 1:

The patent creates a continuous herbicidal action through the synergistic combination of glufosinate and PPO inhibitors, where the two modes of action work together to provide prolonged weed control. The specific formulation ratios ensure that the herbicidal effect continues effectively over an extended period, addressing the inadequate duration of action.

Inventive Principle:
Principle #20Continuity of useful action

4Reliability

If higher application rates of PPO-inhibitor are used to improve effectiveness, then herbicidal activity increases, but the cost and environmental impact increase

Engineering Contradiction:
Improveherbicidal effectivenessVSAvoidapplication rates of PPO-inhibitor
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The patent applies partial action by using reduced amounts of PPO-inhibitor (5-50% of the formulation) in combination with glufosinate. This partial use of the PPO-inhibitor, rather than relying on high doses alone, achieves effective herbicidal control while reducing substance loss and environmental impact.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

Glufosinate serves as an intermediary that enhances the effectiveness of lower PPO-inhibitor doses. The combination allows the PPO-inhibitor to work more efficiently at reduced concentrations, decreasing the loss of substance while maintaining high herbicidal effectiveness.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20230075365A1Herbicide combinations comprising glufosinate and selected PPO inhibitors
Publication Date: 2023.03.09 BASF SE
  • US20230075365A1 patent drawing

AI summary

The present invention relates to specific herbicide combinations comprising (i) L-glufosinate and/or salts thereof and (ii) a PPO-inhibitor selected from Acifluorfen, Fomesafen or Lactofen in specific ratios, and to compositions comprising said herbicide combinations in these ratios. The present invention further relates to a method of producing said specific herbicide combinations and compositions comprising said specific herbicide combinations. The present invention also relates to the use of said specific herbicide combinations and compositions comprising said specific herbicide combinations in the field of agriculture, for controlling harmful plants or undesired plant growth, as well as to corresponding methods.