Synergistic L-Glufosinate Combinations for Resistant Weedy Soybean Control

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Solution Overview

Problem

Current herbicidal combinations are inadequate for controlling resistant and persistent weeds like weedy Glycine max, leading to yield loss and pathogen reservoir issues, and often result in additive or antagonistic effects, phytotoxicity, and resistance development.

Innovation Solution

A synergistic herbicidal combination comprising L-glufosinate, salts, or esters, and at least one acetyl CoA carboxylase inhibitor herbicide is applied to control weedy Glycine max, providing effective weed control with reduced herbicide dosage and improved residual effects.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If current herbicidal combinations are used to control weeds, then weed control is achieved, but they are insufficient to control resistant and persistent weeds like weedy Glycine max

Engineering Contradiction:
Improveweed control effectivenessVSAvoidability to control resistant weed species
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines L-glufosinate (which inhibits glutamine synthetase) with acetyl CoA carboxylase inhibitor herbicides (which inhibit fatty acid synthesis) to create a synergistic herbicidal combination. This merging of two different herbicide mechanisms of action provides enhanced control of resistant Glycine genus weeds while maintaining safety for non-target crops.

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If herbicide dosage is increased to control resistant weeds, then weed control effectiveness improves, but phytotoxicity to crops increases

Engineering Contradiction:
Improveweed control effectivenessVSAvoidphytotoxicity to crops
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the parameter of herbicide combination ratios, specifically formulating L-glufosinate at 10-500 g a.i./ha combined with acetyl CoA carboxylase inhibitor herbicides at 1-100 g a.i./ha. This optimized parameter combination achieves effective weed control while maintaining safe levels for non-target crops through synergistic action.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If single herbicide is used to control weeds, then application simplicity is maintained, but resistance development by weeds occurs

Engineering Contradiction:
Improveherbicide application simplicityVSAvoidresistance management
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The patent merges L-glufosinate and acetyl CoA carboxylase inhibitor herbicides into a single combined formulation that targets multiple weed physiological pathways. This combination approach prevents resistance development by simultaneously attacking multiple metabolic processes in the weed, while the formulation maintains ease of application.

Inventive Principle:
Principle #5Merging (Combining)

4Reliability

If herbicidal combinations are used to improve weed control, then weed control effectiveness increases, but the combinations may result in phytotoxicity to crops

Engineering Contradiction:
Improveweed control effectivenessVSAvoidphytotoxicity
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent uses acetyl CoA carboxylase inhibitor herbicides as intermediary compounds that selectively target weed fatty acid synthesis pathways while sparing crop plants. This intermediary mechanism allows the combination to enhance weed control effectiveness while maintaining crop safety through selective toxicity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20250380701A1Herbicidal combinations and a method for controlling undesired vegetation
Publication Date: 2025.12.18 UPL MAURITIUS LTD
  • US20250380701A1 patent drawing

AI summary

The present disclosure relates to a method for controlling unwanted vegetation/weeds. More particularly, the present disclosure relates to a method for controlling weedy Glycine max with synergistic herbicidal combinations comprising L-glufosinate, salts, esters, or combinations thereof and at least one additional herbicide.