Glutamine Derivative Feed Additives for Safer Animal Growth

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Solution Overview

Problem

Current feed additives used in animal husbandry, such as high-level copper agents, high-level zinc agents, and chemically synthesized antibacterial agents, lead to significant side effects like animal toxicity, growth inhibition, and environmental pollution, necessitating the development of safer and more effective alternatives.

Innovation Solution

The use of glutamine derivatives, their racemates, stereoisomers, tautomers, solvates, or feed acceptable salts in animal feed additives, which enhance sensory performance and improve animal production performance without the adverse effects of traditional additives.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If conventional feed additives (high-level copper agents, high-level zinc agents, chemically synthesized antibacterial agents) are used to improve feed utilization and animal production performance, then productivity is improved, but object-affected harmful factors increase due to animal toxicity, growth inhibition, kidney damage, and environmental pollution

Engineering Contradiction:
Improvefeed utilization and animal production performanceVSAvoidanimal toxicity, growth inhibition, kidney damage, environmental pollution
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent changes the chemical parameters of feed additives by using glutamine derivatives with specific molecular structures (formula I) instead of conventional metal-based additives. This parameter change transforms the additive from toxic heavy metals to biocompatible organic compounds, eliminating toxicity while maintaining feed utilization benefits

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs composite molecular structures combining glutamine backbone with various substituent groups (R1, R2, R3, R4) to create a series of derivative compounds. These composite structures provide diverse biological activities and improved feed efficiency without the harmful effects of conventional additives

Inventive Principle:
Principle #40Composite materials

2Productivity

If conventional feed additives are used to enhance animal production performance, then productivity is improved, but reliability deteriorates due to side effects like liver and kidney toxicity, growth inhibition, and drug resistance

Engineering Contradiction:
Improveanimal production performanceVSAvoidanimal health and safety
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The glutamine derivatives act as temporary, non-accumulating additives that are metabolized and excreted by animals without long-term accumulation in tissues. This eliminates the reliability issues associated with persistent heavy metal additives that accumulate in liver and kidney

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent converts the potential harm of excessive nutrient supplementation into benefit by using glutamine derivatives that enhance feed utilization efficiency. Animals receive adequate nutrition without the harmful side effects of conventional high-level additives

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Data Source

PatentUS12516017B2Application of glutamine derivative in preparation of animal feed additive
Publication Date: 2026.01.06 WISORIG TECH PTE LTD
  • US12516017B2 patent drawing
  • US12516017B2 patent drawing
  • US12516017B2 patent drawing

AI summary

Provided herein is an application of a glutamine derivative in preparation of an animal feed additive, specifically, the application of a glutamine derivative the structure of which is shown in the following formula (I) or racemates, stereoisomers, geometric isomers, tautomers, solvates and feed-acceptable salts of the glutamine derivative in animal feed additives. Results of animal breeding tests show that the glutamine derivative or racemates, stereoisomers, geometric isomers, tautomers, solvates, feed acceptable salts and other compounds thereof may be used as animal feed additives and have good effects in improving animal growth, feed conversion and other production performances.