Glycemic Load Reduction Composition for Sleep Quality
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Solution Overview
Problem
Current understanding of the link between evening dietary carbohydrates and sleep quality is limited, with no clear evidence on how evening meal composition affects next-day cognitive and mood performance, and existing solutions do not effectively promote better sleep quality by lowering glycemic response.
Innovation Solution
Administering a composition with ingredients such as tryptophan, mulberry extract, or glucosidase inhibitors at a predetermined time before or with an evening meal to reduce glycemic load, combining with the meal to achieve a glycemic load of 0.0 to 45.0, thereby promoting better sleep quality and subsequent behavioral outcomes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If conventional evening meals are consumed without intervention, then normal dietary intake is maintained, but sleep quality is compromised due to high glycemic response
Solution Approach 1:
The patent introduces a composition containing specific ingredients (such as chromium, magnesium, zinc, vitamin D, or probiotics) as intermediary substances that mediate between the evening meal and sleep quality. These ingredients act as modifiers that reduce the harmful glycemic response while preserving the beneficial effects of normal dietary intake, thereby improving sleep quality without requiring dietary restriction.
Solution Approach 2:
The patent modifies the glycemic parameters of the evening meal by adding a composition that changes the metabolic response to carbohydrates. This parameter change approach involves altering the glycemic index or glycemic load through the addition of functional ingredients, transforming the meal's impact on blood glucose levels to be more compatible with sleep physiology.
2Reliability
If dietary carbohydrates are reduced to lower glycemic response, then sleep quality improves, but energy intake and satiety are compromised
Solution Approach 1:
The composition serves as an intermediary that allows maintenance of adequate carbohydrate intake while preventing excessive glycemic spikes. The functional ingredients in the composition (such as chromium for insulin sensitivity or magnesium for glucose metabolism) act as mediators that enable the body to handle carbohydrates more efficiently, preserving energy intake while improving sleep quality.
Solution Approach 2:
Rather than reducing the quantity of carbohydrates, the patent changes the metabolic parameters of carbohydrate handling through the added composition. This allows full dietary intake to be maintained while the glycemic response is modified through improved insulin sensitivity, glucose uptake, or metabolic regulation mechanisms provided by the composition ingredients.
3Adaptability or versatility
If no intervention is applied to evening meals, then dietary flexibility is maintained, but next-day cognitive and mood performance suffer due to poor sleep quality
Solution Approach 1:
The composition acts as a bridge that preserves dietary flexibility while improving next-day performance. By adding this intermediary substance to the evening meal, individuals can maintain their preferred dietary choices and flexibility without compromising sleep quality, which in turn improves cognitive and mood performance the next day through better sleep.
Solution Approach 2:
The patent segments the evening meal into two components: the original meal (maintaining dietary flexibility) and the added composition (providing sleep benefits). This segmentation allows the meal to serve dual purposes - satisfying dietary preferences while the composition component addresses sleep quality, thereby improving next-day performance without restricting dietary choices.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The described method effectively improves sleep quality by reducing nocturnal glycemia and enhancing sleep efficiency, duration, and next-day cognitive and mood benefits, as demonstrated by clinical studies showing significant reductions in postprandial glucose response and improved sleep metrics.
Implementation Method 1
The combination of the composition and the meal has a glycemic load lower than the glycemic load of the meal by itself
Implementation Method 2
administration of a composition at a predetermined time before consumption of a meal and/or concurrently with consumption of a meal
Implementation Method 3
The described method effectively improves sleep quality by reducing nocturnal glycemia and enhancing sleep efficiency, duration, and next-day cognitive and mood benefits
Data Source
AI summary
An aspect is a method of improving sleep quality and/or subsequent behavioural outcomes. Another aspect is a method of treating, preventing, and/or reducing at least one of risk, incidence or severity of at least one condition for which improved sleep quality is beneficial. The methods include orally administering a composition to an individual at a predetermined time before consumption of a meal and/or concurrently with consumption of a meal. The combination of the composition and the meal has a glycemic load that is lower than that of the meal and about 0.0 to about 45.0. Preferably the meal is a balanced evening meal, and the composition is a food, a supplement, or a liquid beverage, for example a ready to drink beverage or a beverage reconstituted from a powder. The composition can contain one or more of tryptophan, a glucosidase inhibitor, arginine-proline (AP) dipeptide, a fiber, a resistant starch, a beta-glucan, A-cyclodextrin, glucosidase, a polyphenol, or an amylase inhibitor.